Zobrazeno 1 - 10
of 53
pro vyhledávání: '"J C, van Breda Vriesman"'
Publikováno v:
Scandinavian Journal of Immunology. 56:353-360
Maturation arrest and interference with selection are two well-documented effects of cyclosporin-A (CsA) on the thymus. We recently hypothesized that these effects are related and owing to the reduced T-cell receptor (TCR)-CD3 complex-mediated signal
Publikováno v:
Journal of Experimental Animal Science. 41:22-26
Summary Animal models have been shown to be very valuable in the elucidation of pathologic mechanisms in complex human diseases. However, conscientious comparison with the human disease is required to define to what extend the respective model is rel
Publikováno v:
Journal of Leukocyte Biology. 64:803-809
The CD28-CD80/CD86 costimulatory pathway provides a critical signal for T cell activation. Only recently rat CD80 and CD86 have been cloned and monoclonal antibodies have been generated. In this study we examined the expression of these molecules in
Publikováno v:
Clinical and Experimental Immunology. 113:333-338
SUMMARYLethally irradiated LEW rats reconstituted with syngeneic bone marrow and given CsA for a 4-week period develop a graft-versus-host-like disease upon withdrawal of CsA. This T cell-mediated autoimmune disease is referred to as CsA-induced auto
Publikováno v:
American Journal of Kidney Diseases. 31:962-970
To determine the natural history in early immunoglobulin A (IgA) nephropathy, we evaluated the long-term follow-up of 27 normotensive nonazotemic adult idiopathic IgA nephropathy patients with chronic hematuria who derived from a prospective regional
Autor:
Johannes M. T. Draaisma, Rolien de Jong, Frédéric Altare, Peter J. Kabel, Inez-Anne Haagen, Jaap T. van Dissel, Peter J. C. van Breda Vriesman, Tjitske de Boer, Jean-Laurent Casanova, Diënne G. Elferink, Frank P. Kroon, Tom H. M. Ottenhoff
Publikováno v:
Science. 280:1435-1438
Interleukin-12 (IL-12) is a cytokine that promotes cell-mediated immunity to intracellular pathogens by inducing type 1 helper T cell (TH1) responses and interferon-γ (IFN-γ) production. IL-12 binds to high-affinity β1/β2 heterodimeric IL-12 rece
Autor:
Jan J.G.M. Verschuuren, A. Degenhardt, Jerome B. Posner, M. De Baets, Yvo F. Graus, P. J. C. Van Breda Vriesman, Dennis R. Burton, Josep Dalmau
Publikováno v:
Journal of Neuroimmunology. 82:200-209
Antibodies against the HuD antigen expressed in small-cell lung cancer (SCLC) cross-react with proteins expressed in neurons of the central and peripheral nervous system and are associated with paraneoplastic encephalomyelitis and sensory neuropathy
Publikováno v:
Clinical and Experimental Immunology. 110:79-85
SUMMARY Lethally x-irradiated Lewis rats, reconstituted with syngeneic bone marrow and transiently treated with CsA for 4 weeks, will develop an autoimmune disease about 2–3 weeks after cessation of CsA therapy. CsA-induced autoimmunity is a thymus
Autor:
Mihovil Roglic, J. Damoiseaux, Argyrios N. Theofilopoulos, P. J. C. Van Breda Vriesman, Leo J.J. Beijleveld
Publikováno v:
Transplantation. 62:1468-1476
Lethally irradiated Lewis rats reconstituted with syngeneic bone marrow and given cyclosporine for 4 weeks develop a graft-versus-host-like disease upon withdrawal of CsA. Autoreactive T cells inducing this thymus-dependent autoimmune disease, termed
Autor:
Flip A. Klatter, C. P. M. Broeren, J. G. M. C. Damoiseaux, L. J. J. Beijleveld, P. J. C. Van Breda Vriesman, Jaap Kampinga, Herman Groen
Publikováno v:
Clinical and Experimental Immunology. 105:486-496
Lethally irradiated Lewis (LEW) rats reconstituted with syngeneic bone marrow and given CsA for a 4-week period, develop, upon withdrawal of CsA, a graft-versus-host-like disease, so-called CsA-induced autoimmunity (CsA-AI). This T cell-mediated auto