Zobrazeno 1 - 10
of 25
pro vyhledávání: '"J C, Theiss"'
Autor:
James L Ivett, B Jessen, Bhasker Shetty, C C Capen, T E Ryan, R Gasser, Gregory J. Stevens, J C Theiss, Leigh Ann Burns-Naas, R M McClain, G Furman, W Evering, Mark Zorbas, E Wu, J C Cook, Stephanie Webber, M Chen
Publikováno v:
Humanexperimental toxicology. 24(12)
The carcinogenic potential of nelfinavir mesylate (nelfinavir) was evaluated in a 2-year oral (gavage) study on Sprague-Dawley rats at dose levels of 0 (control), 0 (vehicle control), 100, 300 and 1000 mg/kg per day. At the end of the treatment, incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f26c16a3607fe5464da333fc5d34f14b
https://pubmed.ncbi.nlm.nih.gov/16408618
https://pubmed.ncbi.nlm.nih.gov/16408618
Autor:
J. C. Theiss, D. K. Monteith
Publikováno v:
Drug and chemical toxicology. 19(1-2)
Tacrine is the first drug approved for the treatment of Alzheimer's disease. Approximately 50% of patients treated with tacrine develop elevated serum aminotransferase levels, an indication of potential hepatotoxicity. The mechanism of human hepatoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869319ae648968aa8df77a662eace7d8
https://pubmed.ncbi.nlm.nih.gov/8804553
https://pubmed.ncbi.nlm.nih.gov/8804553
Autor:
J. C. Theiss, G. Krishna
Publikováno v:
Environmental and molecular mutagenesis. 25(4)
Simultaneous assessment of in vivo micronucleus and chromosome aberration endpoints has been described in the rat and the mouse. Bone marrow and spleen cells were utilized for genotoxicity assessment. A cellulose column methodology was used in the mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21b0c305d014525b989904cf027aafa
https://pubmed.ncbi.nlm.nih.gov/7607186
https://pubmed.ncbi.nlm.nih.gov/7607186
Autor:
J A, Benvenuto, T H, Connor, D K, Monteith, J L, Laidlaw, S C, Adams, T S, Matney, J C, Theiss
Publikováno v:
Journal of pharmaceutical sciences. 82(10)
Chemical methods for the degradation of 11 antineoplastic drugs [etoposide, teniposide, bleomycin, mitomycin C, cisplatin, cis-dichloro-trans-dihydroxy-bis(isopropylamine) platinum IV (CHIP), cyclophosphamide, ifosfamide, carmustine, lomustine, and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75e8307cec1df16dc7127e4098ce7860
https://pubmed.ncbi.nlm.nih.gov/8254498
https://pubmed.ncbi.nlm.nih.gov/8254498
Publikováno v:
Cancer research. 44(4)
The ability of the physiologically essential divalent metals calcium and magnesium to inhibit the tumorigenic activities of lead and nickel towards the lungs of strain A mice was investigated. The tumorigenic salts lead(II) subacetate and nickel(II)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e3828d1e2e47a62d92b1a825c8832b8
https://pubmed.ncbi.nlm.nih.gov/6704965
https://pubmed.ncbi.nlm.nih.gov/6704965
Publikováno v:
American journal of hospital pharmacy. 39(11)
Uptake of mutagenic substances by persons handling injectable antineoplastic agents was studied, and various methods of preventing such exposure were evaluated. Six persons who prepared i.v. admixtures individually collected their urine in 24-hour ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0f05f4d2d30d5805e4202af3ce4e5c81
https://pubmed.ncbi.nlm.nih.gov/6756133
https://pubmed.ncbi.nlm.nih.gov/6756133
Publikováno v:
Cancer research. 40(1)
Lactate dehydrogenase virus is the third in a series of viruses which have been examined for the capacity to alter chemically induced mouse lung tumorigenesis. This virus was given to strain A mice by i.p. injection either 4 weeks before, on the same
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a0289f3ff7d94e6d96c9954d20e47fb
https://pubmed.ncbi.nlm.nih.gov/7349905
https://pubmed.ncbi.nlm.nih.gov/7349905
Publikováno v:
Cancer research. 37(1)
An in vitro-in vivo system for screening potentially effective drugs against solid tumors is described. Drug toxicity to plateau-phase pulmonary adenoma cells is used as an in vitro screen for potential activity against solid tumors, since both plate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb9f75ca6c72f7d5b321be24a21c0e23
https://pubmed.ncbi.nlm.nih.gov/830416
https://pubmed.ncbi.nlm.nih.gov/830416
Publikováno v:
American journal of hospital pharmacy. 42(11)
The permeability of four types of protective-clothing material to seven injectable antineoplastic drugs was studied. The protective materials tested were Saranex-laminated Tyvek, polyethylene-coated Tyvek, nonporous Tyvek, and Kaycel. Circles 6 cm in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bef313f12d6c3f64f262f54ef1b29d49
https://pubmed.ncbi.nlm.nih.gov/4073061
https://pubmed.ncbi.nlm.nih.gov/4073061
Autor:
J C, Theiss
Publikováno v:
Cytobios. 29(115-116)
In two in vivo experiments, low doses of 5-methyl cytidine significantly suppressed the growth of urethan-induced lung tumours in strain A mice while higher doses were less effective. This inverse dose-response relationship mimics the previously repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::82cd86b6370a66465f7407600e31868e
https://pubmed.ncbi.nlm.nih.gov/7471817
https://pubmed.ncbi.nlm.nih.gov/7471817