Výsledky vyhledávání - "J C, Tercero"

Circulating tumor cells predict progression free survival and overall survival in patients with relapsed/recurrent advanced ovarian cancer

Autor: Bradley J. Monk, Stanley B. Kaye, Claudia Lebedinsky, Songbai Wang, P. Zintl, Trilok V. Parekh, Andres Poveda, Deborah Ricci, J. C. Tercero, Robert McCormack

Publikováno v: Gynecologic Oncology. 122:567-572

Serial circulating tumor cell (CTC) counts have demonstrated predictive and prognostic value in patients with metastatic breast, colorectal, and prostate cancer. In a phase III study of pegylated liposomal doxorubicin (PLD) with trabectedin vs. PLD f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::280b31bdebc25c8e9bdf8f14beac8a14
https://doi.org/10.1016/j.ygyno.2011.05.028

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Trabectedin in myxoid liposarcomas (MLS): a long-term analysis of a single-institution series

Autor: Palma Dileo, Paola Collini, Roberta Sanfilippo, S. Pilotti, J. Jimeno, J. C. Tercero, Carlo Morosi, Emanuela Virdis, Paolo G. Casali, C. Piovesan, Maurizio D'Incalci, Alessandro Gronchi, Federica Grosso

Publikováno v: Annals of Oncology. 20:1439-1444

Background Trabectedin has been approved in Europe as second-line therapy for advanced soft tissue sarcomas. A previous analysis showed that myxoid liposarcomas (MLS) are particularly sensitive to the drug. We report on the long-term efficacy of trab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1462b26d809a97770bdbcc0343ac260
https://doi.org/10.1093/annonc/mdp004

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Phase II clinical trial of neoadjuvant trabectedin in patients with advanced localized myxoid liposarcoma

Autor: Jean-Yves Blay, Binh Bui, George D. Demetri, S. Pilotti, Antonio Nieto, Elena Tamborini, S. Bonvalot, Pilar Lardelli, Vicente Alfaro, J. C. Tercero, A. Le Cesne, Peter Hohenberger, Raymond J. Hohl, Alessandro Gronchi, I. Perez, Silvia Ferrari

Publikováno v: Annals of oncology : official journal of the European Society for Medical Oncology. 23(3)

Background To evaluate neoadjuvant trabectedin (1.5 mg/m2 24-h i.v. infusion every 3 weeks; three to six cycles) in patients with locally advanced myoxid liposarcoma (ML) previously untreated with chemotherapy or radiation. Patients and methods Prima

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e9c5380b3cce9391ec309bd0aca1ae
https://pubmed.ncbi.nlm.nih.gov/21642514

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Predictive impact of DNA repair functionality on clinical outcome of advanced sarcoma patients treated with trabectedin: a retrospective multicentric study

Autor: Robert G. Maki, Andres Poveda, J. C. Tercero, Federica Grosso, Paolo G. Casali, Rafael Rosell, Miquel Taron, A. Le Cesne, Robin L. Jones, Patrick Schöffski, Antonio Nieto, R. Sanfilipio, J.-Y. Blay, J. Jimeno

Publikováno v: European journal of cancer (Oxford, England : 1990). 47(7)

Aim Trabectedin sensitivity is increased in cells with functional nucleotide excision DNA repair, whereas efficient homologous recombination repair leads to resistance. On this basis, a retrospective study of mRNA expression of BRCA1 (breast cancer s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbab0f9534b64fc7d7807c7b1c7cda0c
https://pubmed.ncbi.nlm.nih.gov/21376569

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MAK3 encodes an N-acetyltransferase whose modification of the L-A gag NH2 terminus is necessary for virus particle assembly

Autor: J C Tercero, Reed B. Wickner

Publikováno v: Journal of Biological Chemistry. 267:20277-20281

The MAK3 gene is necessary for propagation of the L-A double-stranded RNA virus of Saccharomyces cerevisiae. MAK3 encodes a protein with substantial homology to the Escherichia coli rimI N-acetyltransferase that acetylates the NH2 terminus of ribosom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bb1c700ca21e304e0d589978b4cbd07f
https://doi.org/10.1016/s0021-9258(19)88697-0

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Localized mutagenesis and evidence for post-transcriptional regulation of MAK3. A putative N-acetyltransferase required for double-stranded RNA virus propagation in Saccharomyces cerevisiae

Autor: L E Riles, Reed B. Wickner, J C Tercero

Publikováno v: Journal of Biological Chemistry. 267:20270-20276

The MAK3 gene of Saccharomyces cerevisiae is necessary for the propagation of the L-A double-stranded RNA virus and its satellites, such as M1 that encodes a killer toxin. We cloned the MAK3 gene based on its genetic map position using physically map

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45584e5b1bd77c6ef2067870eb20e032
https://doi.org/10.1016/s0021-9258(19)88696-9

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rpoB mutations as an epidemiologic marker in rifampin-resistant Mycobacterium tuberculosis

Autor: F, Chaves, M, Alonso-Sanz, M J, Rebollo, J C, Tercero, M S, Jimenez, A R, Noriega

Publikováno v: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. 4(8)

Cases of rifampin-resistant Mycobacterium tuberculosis from the prison population in Madrid and from the general population in Spain.To identify the rpoB mutations associated with resistance to rifampin and to investigate rpoB genotyping as an epidem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a21a2e70db87c490617b72a1c7bf3d7b
https://pubmed.ncbi.nlm.nih.gov/10949329

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Simple and rapid detection of Mycobacterium tuberculosis complex organisms in bovine tissue samples by PCR

Autor: J. Alemany, Guillermo Suárez, Ernesto Liebana, M Vilafranca, Alicia Aranaz, Mariano Domingo, E Gomez-Mampaso, Ana Mateos, Lucas Domínguez, J C Tercero

Publikováno v: Universitat Autònoma de Barcelona
Europe PubMed Central
Scopus-Elsevier

Mycobacterium bovis is a slowly growing microorganism, and confirmation of the diagnosis by conventional culture is a lengthy process. A simple, rapid method for the extraction of DNA from bovine tissue samples was developed and used in a PCR designe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e474de9e95ce4b3d601918d1bacb453
https://pubmed.ncbi.nlm.nih.gov/7699061

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Final results of a phase II trial of trabectedin (T) in triple-negative, HER2-positive, and BRCA1/2 germ-line-mutated metastatic breast cancer (MBC) patients (pts)

Autor: Jan Lubinski, Joanne L. Blum, J. C. Tercero, K. L. Tedesco, Frankie A. Holmes, A. Goncalves, Pilar Lardelli, Suzette Delaloge, Cynthia Osborne, A. Florez

Publikováno v: Journal of Clinical Oncology. 29:1125-1125

1125 Background: Single-agent T has shown antitumor activity in pts with pretreated MBC. Preclinical data suggested T displays increased activity in cell lines having intact nucleotide excision repair (NER), evidenced in particular by XPG expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5cf99f8077df2efe06804539de7f6a40
https://doi.org/10.1200/jco.2011.29.15_suppl.1125

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