Výsledky vyhledávání - "J C, Swinkels"

Dissociation of heparin-dependent thrombin and factor Xa inhibitory activities of antithrombin-III by mutations in the reactive site

Autor: H J, Theunissen, R, Dijkema, P D, Grootenhuis, J C, Swinkels, T L, de Poorter, P, Carati, A, Visser

Publikováno v: The Journal of biological chemistry. 268(12)

Antithrombin-III (AT-III) is a heparin-dependent inhibitor of thrombin and Factor Xa, two serine proteases that are crucial for blood coagulation. In order to assess whether it would be possible to target AT-III only towards Factor Xa, we replaced pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bd38590fdfcca5602462e1d9dfb18b0e
https://pubmed.ncbi.nlm.nih.gov/8473344

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