Výsledky vyhledávání - "J C, Scarlett"

Growth hormone (GH) receptor blockade with a PEG-modified GH (B2036-PEG) lowers serum insulin-like growth factor-I but does not acutely stimulate serum GH

Autor: M O, Thorner, C J, Strasburger, Z, Wu, M, Straume, M, Bidlingmaier, S S, Pezzoli, K, Zib, J C, Scarlett, W F, Bennett

Publikováno v: The Journal of clinical endocrinology and metabolism. 84(6)

B2036-PEG, a GH receptor (GH-R) antagonist, is an analog of GH that is PEG-modified to prolong its action. Nine mutations alter the binding properties of this molecule, preventing GH-R dimerization and GH action. A potential therapeutic role of B2036

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::81ba5932f131bd3d57440aee1b4f2c9c
https://pubmed.ncbi.nlm.nih.gov/10372717

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