Zobrazeno 1 - 10
of 23
pro vyhledávání: '"J C, Love"'
Autor:
S. Manier, J. Park, M. Capelletti, M. Bustoros, S. S. Freeman, G. Ha, J. Rhoades, C. J. Liu, D. Huynh, S. C. Reed, G. Gydush, K. Z. Salem, D. Rotem, C. Freymond, A. Yosef, A. Perilla-Glen, L. Garderet, E. M. Van Allen, S. Kumar, J. C. Love, G. Getz, V. A. Adalsteinsson, I. M. Ghobrial
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Circulating tumor cells (CTCs) and cell-free DNA (cfDNA) enables characterization of a patient’s cancer. Here, the authors analyse CTCs, cfDNA, and tumor biopsies from multiple myeloma patients to show these approaches are complementary for mutatio
Externí odkaz:
https://doaj.org/article/152a39cf0415407e9126a36af80c7f2a
Autor:
Chaz Goodwine, Wu Sl, Catherine Bartlett Matthews, J. C. Love, Cvetkovic A, Nicholas J. Mozdzierz, Steven M. Timmick, Craig A. Mascarenhas, Kartik A. Shah, Kerry R. Love, Amos E. Lu, Alexandra D. Bonnyman, Nicholas Vecchiarello, William S. Hancock, Doherty W, Wang Ya, Richard D. Braatz, Clark Jj, Di Wu, Laura E. Crowell, Liu Y, Neil C. Dalvie, Steven M. Cramer, Liu D, Bradbury L, Brady, Noelle Colant, Alan Stockdale
Publikováno v:
Nature biotechnology
PMC
PMC
A benchtop system for protein synthesis achieves purity and potency comparable to those of marketed drugs. Conventional manufacturing of protein biopharmaceuticals in centralized, large-scale, single-product facilities is not well-suited to the agile
Autor:
Shaji Kumar, Samuel S. Freeman, Laurent Garderet, Gavin Ha, J. C. Love, Irene M. Ghobrial, Karma Salem, Marzia Capelletti, Sarah C. Reed, Claudia Freymond, E.M. Van Allen, Denisse Rotem, Gad Getz, Adriana Perilla-Glen, Salomon Manier, Mark Bustoros, Viktor A. Adalsteinsson, Daisy Huynh, Justin Rhoades, Amir Yosef, Gregory Gydush, Joel Park, Chia Jen Liu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications
Liquid biopsies including circulating tumor cells (CTCs) and cell-free DNA (cfDNA) have enabled minimally invasive characterization of many cancers, but are rarely analyzed together. Understanding the detectability and genomic concordance of CTCs and
Autor:
Patrick Swann, J. C. Love, Richard D. Braatz, Kristen A. Severson, Helena Madden, Mo Jiang, Li Zang
Publikováno v:
Biotechnology and Bioengineering. 114:2445-2456
Real-time release testing (RTRT) is defined as "the ability to evaluate and ensure the quality of in-process and/or final drug product based on process data, which typically includes a valid combination of measured material attributes and process con
Autor:
Madhvi Menon, Tanina D. Cadwell, Manolis Kellis, Brittany A. Goods, Yu Xing, Brian P. Hafler, Anat Stemmer-Rachamimov, J. C. Love, Jose Davila-Velderrain, Shahin Mohammadi, Alex K. Shalek
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Menon, M, Mohammadi, S, Davila-Velderrain, J, Goods, B A, Cadwell, T D, Xing, Y, Stemmer-Rachamimov, A, Shalek, A K, Love, J C, Kellis, M & Hafler, B P 2019, ' Single-cell transcriptomic atlas of the human retina identifies cell types associated with age-related macular degeneration ', Nature Communications, vol. 10, no. 1, pp. 4902 . https://doi.org/10.1038/s41467-019-12780-8
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Menon, M, Mohammadi, S, Davila-Velderrain, J, Goods, B A, Cadwell, T D, Xing, Y, Stemmer-Rachamimov, A, Shalek, A K, Love, J C, Kellis, M & Hafler, B P 2019, ' Single-cell transcriptomic atlas of the human retina identifies cell types associated with age-related macular degeneration ', Nature Communications, vol. 10, no. 1, pp. 4902 . https://doi.org/10.1038/s41467-019-12780-8
Genome-wide association studies (GWAS) have identified genetic variants associated with age-related macular degeneration (AMD), one of the leading causes of blindness in the elderly. However, it has been challenging to identify the cell types associa
Autor:
Alex K. Shalek, Berta Almoguera, George Hripcsak, Maria C. Garzon, Christine T. Lauren, Travis K. Hughes, J. C. Love, E. Dabela, Josh C. Denny, Hakon Hakonarson, Krzysztof Kiryluk, Z. Dai, C. Wang, John Connolly, P. Sleiman, Lynn Petukhova, Chunhua Weng, Iuliana Ionita-Laza, Azim J. Khan, J. McGovern, L.E. Levin, Frank D. Mentch, M. Hayes, Z. Yang
Publikováno v:
Journal of Investigative Dermatology. 141:S99
Autor:
Hao-Wei Su, Joel Voldman, Darrell J. Irvine, J. C. Love, Marc Castellarnau, Talar Tokatlian, Gregory L. Szeto
Publikováno v:
PMC
This study presents stochastic particle barcoding (SPB), a method for tracking cell identity across bioanalytical platforms. In this approach, single cells or small collections of cells are co-encapsulated within an enzymatically-degradable hydrogel
Publikováno v:
Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering. 215:1241-1244
Each year, automotive manufacturers spend the equivalent of millions of pounds sterling on measuring the paint surface defect known as ‘orange peel’. This paper uncovers the near invisibility of orange peel to customers and questions the need for
Publikováno v:
Ultrasound in Obstetrics and Gynecology. 18:39-43
Background Cardiac anomalies may be associated with abnormal coronary vascular connections. We report the prenatal diagnosis of ventriculocoronary fistula in three fetuses with associated cardiac anomalies. Materials and Methods Fetal echocardiograph