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Autor:
J C, Kucharczuk, B, Randazzo, M Y, Chang, K M, Amin, A A, Elshami, D H, Sterman, N P, Rizk, K L, Molnar-Kimber, S M, Brown, A R, MacLean, L A, Litzky, N W, Fraser, S M, Albelda, L R, Kaiser
Publikováno v:
Cancer research. 57(3)
Modified, nonneurovirulent herpes simplex viruses (HSVs) have shown promise in the treatment of brain tumors. However, HSV-1 can infect and lyse a wide range of cell types. In this report, we show that HSV-1716, a mutant lacking both copies of the ge