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pro vyhledávání: '"J C, Kapeghian"'
Publikováno v:
Toxicological Sciences. 35:197-204
Many marketed pharmaceuticals are known to cause idiosyncratic agranulocytosis in humans. Similarly prinomide, an antiinflammatory drug, was associated with a low incidence of agranulocytosis ( 90%; 2 min); this reaction was dependent on H2O2and MPO
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 35(2)
Many marketed pharmaceuticals are known to cause idiosyncratic agranulocytosis in humans. Similarly prinomide, an antiinflammatory drug, was associated with a low incidence of agranulocytosis (0.3%) in clinical trials, even though chronic toxicity st
Publikováno v:
NMR in biomedicine. 4(1)
The progression of carbon tetrachloride-induced liver damage, determined by 31P NMR spectroscopy, was compared with selected serum enzyme and histological changes in rats. ATP levels declined as early as 8 h post-CCI4 administration, with partial rec
Autor:
J C, Kapeghian, A J, Verlangieri
Publikováno v:
Journal of medical primatology. 13(2)
Primaquine phosphate treatment (0.5 mg/kg/day, per os [p.o.], 14 days) significantly increased values for serum sodium, potassium, and uric acid, while calcium levels were decreased in male Macaca fascicularis. Serum values returned to baseline (pret
Publikováno v:
Journal of medical primatology. 13(5)
Normal serum values for alkaline phosphatase were significantly higher in juvenile male cynomolgus monkeys compared to adults. Conversely, blood urea nitrogen (BUN) was significantly lower in juveniles than adults. A comparison of selected EKG parame
Publikováno v:
Laboratory animal science. 35(1)
Selected serum enzymes, cholesterol, triglycerides, glucose, uric acid, protein, albumin, bilirubin, BUN, hematology, and electrocardiograms (EKG) were obtained from adult male cynomolgus (Macaca fascicularis) and adult male stumptailed (Macaca arcto