Zobrazeno 1 - 6
of 6
pro vyhledávání: '"J C, Cheetham"'
Publikováno v:
Journal of molecular biology. 235(3)
Two-dimensional 1H nuclear magnetic resonance spectroscopy has been used to examine the complexes formed in solution between hen egg-white lysozyme and N-acetylglucosamine (GlcNAc) oligosaccharides. Changes in chemical shift have been measured for re
Publikováno v:
Journal of molecular biology. 224(3)
The structure of the tri-N-acetylchitotriose inhibitor complex of hen egg-white lysozyme has been refined at 1.75 A resolution, using data collected from a complex crystal with ligand bound at less than full occupancy. To determine the exact value of
Publikováno v:
Methods in enzymology. 203
Publikováno v:
Methods in enzymology. 203
Each of the six CDRs of Gloop2 is shown with the modeled structure in. Overall, the results obtained using the combined algorithm are similar in accuracy to those achieved using the canonical method of Chothia et al. However, the canonical method is
Publikováno v:
Biochemical Society symposium. 57
For maximum value, a predicted model of an antibody-combining site should have an accuracy approaching that of an X-ray structure (1.6-2.7 A). In addition, the method by which the combining site is modelled should make no demands on the user of a sor
Publikováno v:
Journal of molecular biology. 190(3)
Molecular dynamics simulations of hen egg-white lysozyme in the free and substrate-bound states are reported and the nature of the average structures and atomic fluctuations are analyzed. Crystallographic water molecules of structural importance, as