Zobrazeno 1 - 10
of 11
pro vyhledávání: '"J C, Alers"'
Publikováno v:
Anticancer research. 21(6A)
The incidence of adenocarcinomas of the distal esophagus (Barrett's esophagus) and proximal stomach (gastric cardia) has increased rapidly over the past decades. In contrast to this dramatic increase, genetic knowledge is sparse.We investigated genom
Publikováno v:
Cancer research. 61(7)
The incidence of adenocarcinoma in Barrett's esophagus has been increasing rapidly over the past decades. Neoplastic progression is characterized by three well-defined premalignant stages: metaplasia, low-grade dysplasia, and high-grade dysplasia. A
Autor:
N C, Naus, E, van Drunen, A, de Klein, G P, Luyten, D A, Paridaens, J C, Alers, B R, Ksander, H B, Beverloo, R M, Slater
Publikováno v:
Genes, chromosomescancer. 30(3)
Several nonrandom recurrent chromosomal changes are observed in uveal melanoma. Some of these abnormalities, e.g., loss of chromosome 3, gain of the q arm of chromosome 8, and chromosome 6 abnormalities, are of prognostic value. Cytogenetic analysis
Autor:
J C, Alers, P J, Krijtenburg, A N, Vis, R F, Hoedemaeker, M F, Wildhagen, W C, Hop, T T, van Der Kwast, F H, Schröder, H J, Tanke, H, van Dekken
Publikováno v:
The American journal of pathology. 158(2)
No objective parameters have been found so far that can predict the biological behavior of early stages of prostatic cancer, which are encountered frequently nowadays due to surveillance and screening programs. We have applied comparative genomic hyb
Publikováno v:
The Journal of pathology. 192(2)
The worldwide incidence of hepatocellular carcinoma (HCC) is approximately one million cases a year. This makes HCC one of the most frequent human malignancies, especially in Asia and Africa, although the incidence is increasing also in the western w
Autor:
J M, Kros, P R, van Run, J C, Alers, H B, Beverloo, M J, van den Bent, C J, Avezaat, H, van Dekken
Publikováno v:
The Journal of pathology. 188(3)
Four low-grade oligodendrogliomas, nine anaplastic oligodendrogliomas and two mixed oligoastrocytomas were investigated for chromosomal aberrations by comparative genomic hybridization on formalin-fixed, paraffin-embedded tissue samples. The most fre
Publikováno v:
Genes, chromosomescancer. 25(3)
Comparative genomic hybridization (CGH) has become a powerful technique for studying gains and losses of DNA sequences in solid tumors. Importantly, DNA derived from archival tumor tissue is also applicable in CGH analysis. However, DNA isolated from
Autor:
J C, Alers, P J, Krijtenburg, W C, Hop, W A, Bolle, F H, Schröder, T H, van der Kwast, F T, Bosman, H, van Dekken
Publikováno v:
The Journal of pathology. 185(3)
Only limited data are available on chromosomes specifically involved in prostatic tumour progression. This study has evaluated the cytogenetic status of primary prostatic carcinomas, local tumour recurrences, and distant metastases, representing diff
Autor:
J C, Alers, P J, Krijtenburg, C, Rosenberg, W C, Hop, A M, Verkerk, F H, Schröder, T H, van der Kwast, F T, Bosman, H, van Dekken
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 77(5)
Only limited data are available on chromosomes specifically involved in the multistep tumorigenesis of prostate cancer. To investigate the cytogenetic status at different stages of prostatic tumor development, we have applied interphase in situ hybri
Publikováno v:
Cytometry. 26(4)
We investigated the feasibility of automated counting of in situ hybridization signals (ISH) in interphase cells isolated from paraffin embedded prostate tissue. In total, 34 specimens from 7 patients with prostate cancer were stained with probes spe