Zobrazeno 1 - 10
of 240
pro vyhledávání: '"J Burne"'
Autor:
Md. Mamun Al-Amin, Robert K. P. Sullivan, Suzy Alexander, David A. Carter, DanaKai Bradford, Thomas H. J. Burne
Publikováno v:
AIMS Neuroscience, Vol 9, Iss 1, Pp 31-56 (2022)
Vitamin D deficiency is prevalent in adults and is associated with cognitive impairment. However, the mechanism by which adult vitamin D (AVD) deficiency affects cognitive function remains unclear. We examined spatial memory impairment in AVD-deficie
Externí odkaz:
https://doaj.org/article/78c8025aa7e14929bc875bcf420d9e63
Autor:
Marija Kojic, Tomasz Gawda, Monika Gaik, Alexander Begg, Anna Salerno-Kochan, Nyoman D. Kurniawan, Alun Jones, Katarzyna Drożdżyk, Anna Kościelniak, Andrzej Chramiec-Głąbik, Soroor Hediyeh-Zadeh, Maria Kasherman, Woo Jun Shim, Enakshi Sinniah, Laura A. Genovesi, Rannvá K. Abrahamsen, Christina D. Fenger, Camilla G. Madsen, Julie S. Cohen, Ali Fatemi, Zornitza Stark, Sebastian Lunke, Joy Lee, Jonas K. Hansen, Martin F. Boxill, Boris Keren, Isabelle Marey, Margarita S. Saenz, Kathleen Brown, Suzanne A. Alexander, Sergey Mureev, Alina Batzilla, Melissa J. Davis, Michael Piper, Mikael Bodén, Thomas H. J. Burne, Nathan J. Palpant, Rikke S. Møller, Sebastian Glatt, Brandon J. Wainwright
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Subunits of the Elongator complex have been implicated in several nervous system pathologies. Here, the authors identify ELP2 variants in six patients with neurodevelopmental anomalies and show in mouse models that these variants impact protein stabi
Externí odkaz:
https://doaj.org/article/04bbd860a4c34da0ae14a920e50e23e1
Autor:
Joana A. Revez, Tian Lin, Zhen Qiao, Angli Xue, Yan Holtz, Zhihong Zhu, Jian Zeng, Huanwei Wang, Julia Sidorenko, Kathryn E. Kemper, Anna A. E. Vinkhuyzen, Julanne Frater, Darryl Eyles, Thomas H. J. Burne, Brittany Mitchell, Nicholas G. Martin, Gu Zhu, Peter M. Visscher, Jian Yang, Naomi R. Wray, John J. McGrath
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Vitamin D is a precursor of the steroid hormone 1,25-dihydroxyvitamin D3, and its deficiency is associated with many adverse health outcomes. Here, Revez et al. perform a genome-wide association study for circulating 25-hydroxyvitamin D in 417,580 in
Externí odkaz:
https://doaj.org/article/55add9b22a904d64a57de115f29178af
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Schizophrenia is characterized by positive, negative and cognitive symptoms. All current antipsychotic treatments feature dopamine-receptor antagonism that is relatively effective at addressing the psychotic (positive) symptoms of schizophrenia. Howe
Externí odkaz:
https://doaj.org/article/661f9a6820b34ecab5078d528d177dc9
Autor:
Anna A. E. Vinkhuyzen, Darryl W. Eyles, Thomas H. J. Burne, Laura M. E. Blanken, Claudia J. Kruithof, Frank Verhulst, Tonya White, Vincent W. Jaddoe, Henning Tiemeier, John J. McGrath
Publikováno v:
BJPsych Open, Vol 3, Pp 85-90 (2017)
Background There is growing interest in linking vitamin D deficiency with autism spectrum disorders (ASDs). The association between vitamin D deficiency during gestation, a critical period in neurodevelopment, and ASD is not well understood. Aims
Externí odkaz:
https://doaj.org/article/2030e04ebe8e4eb3a2ffc20bb5e8653d
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Psychostimulants, such as amphetamine, are widely used to treat attentional deficits. In humans, response to dopaminergic medications is complex with improvement often dependent on baseline performance. Our goal was to determine if attention
Externí odkaz:
https://doaj.org/article/8ee3c78937ef44f380741d17cb7841f6
Publikováno v:
Molecular and Cellular Biochemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfbe3edfeda32eee5e3d56e55a3090f8
https://doi.org/10.1007/s11010-022-04634-7
https://doi.org/10.1007/s11010-022-04634-7
Publikováno v:
Bio-Protocol, Vol 7, Iss 20 (2017)
Reversal learning can be used to examine deficits in cognitive flexibility, which have been linked to a number of neuropsychiatric disorders including schizophrenia and addiction. However, methods of examining reversal learning have varied substantia
Externí odkaz:
https://doaj.org/article/a4bc95e2c21e467ca64450cfe0f229e1
Autor:
Nyoman D. Kurniawan, Margarita Saenz, Melissa J. Davis, Anna Salerno-Kochan, Julie S. Cohen, Sebastian Glatt, Anna Kościelniak, Ali Fatemi, Mikael Bodén, Martin F. Boxill, Joy Lee, Woo Jun Shim, Nathan J. Palpant, Tomasz Gawda, Jonas K. Hansen, Katarzyna Drożdżyk, Alexander Begg, Rikke S. Møller, Michael Piper, Marija Kojic, Soroor Hediyeh-Zadeh, Thomas H. J. Burne, Brandon J. Wainwright, Kathleen Brown, Isabelle Marey, Sergey Mureev, Rannvá K. Abrahamsen, Enakshi Sinniah, Zornitza Stark, Laura A. Genovesi, Monika Gaik, Andrzej Chramiec-Głąbik, Suzanne Alexander, Alun Jones, Alina Batzilla, Christina Fenger, Camilla Gøbel Madsen, Maria Kasherman, Boris Keren, Sebastian Lunke
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Kojic, M, Gawda, T, Gaik, M, Begg, A, Salerno-Kochan, A, Kurniawan, N D, Jones, A, Drożdżyk, K, Kościelniak, A, Chramiec-Głąbik, A, Hediyeh-Zadeh, S, Kasherman, M, Shim, W J, Sinniah, E, Genovesi, L A, Abrahamsen, R K, Fenger, C D, Madsen, C G, Cohen, J S, Fatemi, A, Stark, Z, Lunke, S, Lee, J, Hansen, J K, Boxill, M F, Keren, B, Marey, I, Saenz, M S, Brown, K, Alexander, S A, Mureev, S, Batzilla, A, Davis, M J, Piper, M, Bodén, M, Burne, T H J, Palpant, N J, Møller, R S, Glatt, S & Wainwright, B J 2021, ' Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype ', Nature Communications, vol. 12, 2678 . https://doi.org/10.1038/s41467-021-22888-5
Kojic, M, Gawda, T, Gaik, M, Begg, A, Salerno-Kochan, A, Kurniawan, N D, Jones, A, Drożdżyk, K, Kościelniak, A, Chramiec-Głąbik, A, Hediyeh-Zadeh, S, Kasherman, M, Shim, W J, Sinniah, E, Genovesi, L A, Abrahamsen, R K, Fenger, C D, Madsen, C G, Cohen, J S, Fatemi, A, Stark, Z, Lunke, S, Lee, J, Hansen, J K, Boxill, M F, Keren, B, Marey, I, Saenz, M S, Brown, K, Alexander, S A, Mureev, S, Batzilla, A, Davis, M J, Piper, M, Bodén, M, Burne, T H J, Palpant, N J, Møller, R S, Glatt, S & Wainwright, B J 2021, ' Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype ', Nature Communications, vol. 12, 2678 . https://doi.org/10.1038/s41467-021-22888-5
Intellectual disability (ID) and autism spectrum disorder (ASD) are the most common neurodevelopmental disorders and are characterized by substantial impairment in intellectual and adaptive functioning, with their genetic and molecular basis remainin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88d1f07cbf7c539d80a6e3ae160ebc4
https://doaj.org/article/04bbd860a4c34da0ae14a920e50e23e1
https://doaj.org/article/04bbd860a4c34da0ae14a920e50e23e1
Publikováno v:
Molecular Neurobiology. 57:2179-2193
Intellectual disability (ID) and autism spectrum disorder (ASD) are two of the most common neurodevelopmental disorders. Both disorders are extremely heterogenous, and only ~ 40% of reported cases have so far been attributed to genetic mutations. Of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c85f58761e7e02d1e2a34a721109168c
https://doi.org/10.1007/s12035-020-01881-x
https://doi.org/10.1007/s12035-020-01881-x