Zobrazeno 1 - 10
of 359
pro vyhledávání: '"J Bradfield"'
Autor:
Julia L. Gross, Rahul Basu, Clinton J. Bradfield, Jing Sun, Sinu P. John, Sanchita Das, John P. Dekker, David S. Weiss, Iain D. C. Fraser
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The immunologic consequences of using bactericidal versus bacteriostatic antibiotic treatments are unclear. We observed a bacteriostatic (growth halting) treatment was more protective than a bactericidal (bacteria killing) treatment in a mur
Externí odkaz:
https://doaj.org/article/5cf8fa006a8a40e3b86d8ef3c745661e
Autor:
Sinu P. John, Anju Singh, Jing Sun, Makheni Jean Pierre, Lulwah Alsalih, Crystal Lipsey, Ziann Traore, Shenavia Balcom-Luker, Clinton J. Bradfield, Jian Song, Tovah E. Markowitz, Margery Smelkinson, Marc Ferrer, Iain D.C. Fraser
Publikováno v:
Cell Reports, Vol 41, Iss 1, Pp 111441- (2022)
Summary: Biologically active small molecules can impart modulatory effects, in some cases providing extended long-term memory. In a screen of biologically active small molecules for regulators of tumor necrosis factor (TNF) induction, we identify sev
Externí odkaz:
https://doaj.org/article/06f3747de2c641e5be2280b4ab2b1065
Autor:
Michael G. Dorrington, Clinton J. Bradfield, Justin B. Lack, Bin Lin, Sinu P. John, Jonathan J. Liang, Tregei Starr, Orna Ernst, Julia L. Gross, Jing Sun, Alexandra H. Miller, Olivia Steele-Mortimer, Iain D. C. Fraser
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8 (2021)
Externí odkaz:
https://doaj.org/article/b3f5ff7be18b4a19aff1127ee699e396
Autor:
Michael G Dorrington, Clinton J Bradfield, Justin B Lack, Bin Lin, Jonathan J Liang, Tregei Starr, Orna Ernst, Julia L Gross, Jing Sun, Alexandra H Miller, Olivia Steele-Mortimer, Iain D C Fraser
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009395 (2021)
The mammalian immune system is constantly challenged by signals from both pathogenic and non-pathogenic microbes. Many of these non-pathogenic microbes have pathogenic potential if the immune system is compromised. The importance of type I interferon
Externí odkaz:
https://doaj.org/article/8b5f8bf5b20d4cddad442adfcadcec1f
Autor:
Clinton J. Bradfield, Jonathan J. Liang, Orna Ernst, Sinu P. John, Jing Sun, Sundar Ganesan, Adriana A. de Jesus, Clare E. Bryant, Raphaela Goldbach-Mansky, Iain D. C. Fraser
Publikováno v:
Cell Death & Differentiation. 30:589-604
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24434289abb0a6998c282dbf4bc4ba59
https://doi.org/10.1038/s41418-022-01106-9
https://doi.org/10.1038/s41418-022-01106-9
Akademický článek
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Autor:
Sinu P. John, Jing Sun, Rebecca J. Carlson, Binh Cao, Clinton J. Bradfield, Jian Song, Margery Smelkinson, Iain D.C. Fraser
Publikováno v:
Cell Reports, Vol 25, Iss 1, Pp 95-106.e6 (2018)
Summary: Activation of the TLR4 signaling pathway by lipopolysaccharide (LPS) leads to induction of both inflammatory and interferon-stimulated genes, but the mechanisms through which these coordinately activated transcriptional programs are balanced
Externí odkaz:
https://doaj.org/article/1d901e420dc14605a801e970fd481093
Publikováno v:
Invasive Plant Science and Management. 14:232-239
Yellow-flag iris (Iris pseudacorus L.) is a nonnative, invasive wetland plant that disrupts riparian ecosystem processes and is widely distributed across the United States and Canada. Due to its physiological and morphological characteristics, I. pse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::407534245802bb54fd1938162821fbb7
https://doi.org/10.1017/inp.2021.28
https://doi.org/10.1017/inp.2021.28
Akademický článek
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Autor:
Isaac Bishof, Iain D. C. Fraser, Arthur Nuccio, Trisha Tucholski, Casey M. Daniels, Clinton J. Bradfield, Nathan P. Manes, Aleksandra Nita-Lazar, Samuel Katz, Pauline R. Kaplan
Publikováno v:
Journal of Proteome Research. 19:3716-3731
We have used mass spectrometry (MS) to characterize protein signaling in lipopolysaccharide (LPS)-stimulated macrophages from human blood, human THP1 cells, mouse bone marrow, and mouse Raw264.7 cells. Protein ADP-ribosylation was truncated down to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3af986325ae7495f8bf54f9aec637d
https://doi.org/10.1021/acs.jproteome.0c00261
https://doi.org/10.1021/acs.jproteome.0c00261