Zobrazeno 1 - 10
of 46
pro vyhledávání: '"J Bomford"'
Autor:
N McKeag, Panos Kottaridis, C Kyriacou, J Bomford, HH McGarrigle, Ratna Chatterjee, David C. Linch, Joseph Eliahoo, Stephen Mackinnon
Publikováno v:
Bone Marrow Transplantation. 31:45-50
Most bone marrow transplant recipients are infertile due to reversible or irreversible testicular failure. However, little is known about the gonadotoxic potential of the newly introduced nonmyeloablative transplants. We undertook a 24-month longitud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26de37954f1a2b97e52e2668033365f5
https://doi.org/10.1038/sj.bmt.1703777
https://doi.org/10.1038/sj.bmt.1703777
Publikováno v:
Diabetes. 41:760-765
Abnormal myoinositol metabolism has been implicated as a contributor to the development of diabetic neuropathy. Furthermore, in vitro glucose inhibits animal and human myoinositol transporters. To investigate whether myoinositol transport is abnormal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c1da87c608649c0f30a7dbacdb958ac
https://doi.org/10.2337/diab.41.6.760
https://doi.org/10.2337/diab.41.6.760
Publikováno v:
Diabetologia. 33:371-377
The development of proteinuria in Type 1 (insulin-dependent) diabetic patients may depend on predisposition to essential hypertension in addition to poor glycaemic control. Previous work has shown increased leucocyte Na+/H+ antiport activity in essen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d39542b46f18966ad5244ea3a7158606
https://doi.org/10.1007/bf00404642
https://doi.org/10.1007/bf00404642
Autor:
N. Ioannou, Christopher I S Meadows, C Langrish, J Bomford, Boris Lams, Luigi Camporota, D Lloyd, W Berry, Guy Glover, M Barry, Nicholas A Barrett, Duncan Wyncoll, A Retter
Publikováno v:
Critical Care
Pulmonary haemorrhage (PH) is common in patients receiving mechanical ventilation and especially during ECMO, due to severe lung pathology and systemic anticoagulation. Whilst PH manifests as worsening ventilation and gas exchange, in ECMO patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fdf989d78dad0eb65e624257a797129
https://doi.org/10.1186/cc14291
https://doi.org/10.1186/cc14291
Publikováno v:
Acta diabetologica. 30(4)
Diabetic neuropathy is associated with abnormalities in lipid metabolism and has been postulated to be associated with abnormal myoinositol metabolism. Leucocyte myoinositol influx was measured using a triple isotope method in long-standing type 1 (i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b067a6d14da114a55cb6b274ebf59e3
https://pubmed.ncbi.nlm.nih.gov/8180415
https://pubmed.ncbi.nlm.nih.gov/8180415
Publikováno v:
Experimental physiology. 77(4)
Prolonged infusion of the beta 2-adrenergic agonist, ritodrine, into sheep during late pregnancy decreased maternal plasma K+ from 3.6 to 2.5 mmol l-1 during the first 6-8 h of infusion, as it does during tocolysis in women. This decrease was not acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61f2582996faa93bac1af3ead80c8c5
https://pubmed.ncbi.nlm.nih.gov/1355975
https://pubmed.ncbi.nlm.nih.gov/1355975
Publikováno v:
Diabetologia. 33(5)
It is uncertain why only one third of Type 1 (insulin-dependent) diabetic patients develop nephropathy. One suggestion is the inheritance of a predisposition to essential hypertension. We have previously found elevated Na+/H+ antiport activity and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915a8f71e967e870869dacfaf551f3f7
http://ora.ox.ac.uk/objects/uuid:7088fc71-8907-4ffb-9552-120411697772
http://ora.ox.ac.uk/objects/uuid:7088fc71-8907-4ffb-9552-120411697772
Publikováno v:
Scopus-Elsevier
1. Low intracellular concentrations of myo-inositol in diabetic cells may contribute to the development of tissue damage. The cause of these low levels is unknown, but inhibition of a putative myo-inositol transporter by high concentrations of glucos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a30ece917edf214208db3715673195
https://pubmed.ncbi.nlm.nih.gov/2156655
https://pubmed.ncbi.nlm.nih.gov/2156655
Publikováno v:
Clinical Science. 78:9P-9P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00de7a7c981e4520cde510c2bc1657a1
https://doi.org/10.1042/cs078009p
https://doi.org/10.1042/cs078009p
Autor:
Leong L. Ng, J Bomford
Publikováno v:
Biochemical Journal. 259:311-314
The Na+/H+ antiport is an important regulator of cellular volume, pH and Na+ concentration in mammalian cells. The stoichiometry of this antiporter has previously been shown to be a 1:1 exchange of internal H+ for external Na+. We have investigated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d6366b970c169234f375657f66e768a
https://doi.org/10.1042/bj2590311
https://doi.org/10.1042/bj2590311