Zobrazeno 1 - 10 of 82 pro vyhledávání: '"J Bolt-de Vries"'
1
Gene expression profiles in circulating tumor cells to predict prognosis in metastatic breast cancer patients
Autor: John W.M. Martens, Anieta M. Sieuwerts, Jaco Kraan, J Bolt-de Vries, P. van der Spoel, Agnes Jager, Bianca Mostert, Marcel Smid, A van Galen, Dieter Peeters, Caroline M. Seynaeve, Stefan Sleijfer, J.A. Foekens, Jan-Willem Gratama, F. E. de Jongh, Jacqueline M. Stouthard, Diederik F. S. Kehrer, Maxime P. Look, Luc Dirix, P. Hamberg
Publikováno v: Annals of oncology
Annals of Oncology, 26(3), 510-516. Elsevier Ltd.
Background: A circulating tumor cell (CTC) count is an established prognostic factor in metastatic breast cancer (MBC). Besides enumeration, CTC characterization promises to improve outcome prediction and treatment guidance. Having shown the feasibil
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246290d61c54e8414446f0ba1eebedc6
https://pubmed.ncbi.nlm.nih.gov/25471333
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2
Prognostic value of tissue-type plasminogen activator (tPA) and its complex with the type-1 inhibitor (PAI-1) in breast cancer
Autor: C.G.J. Sweep, J.G.M. Klijn, Maxime P. Look, J.A. Foekens, J Bolt-de Vries, N. Grebenschikov, T. H. Van Tienoven, J.H. de Witte, J. J. T. M. Heuvel, Th.J. Benraad, H. A. Peters
Publikováno v: British Journal of Cancer, 80, 1/2, pp. 286-294
ResearcherID
British Journal of Cancer
British Journal of Cancer, 80(1/2), 286-294. Nature Publishing Group
British Journal of Cancer, 80, 286-294
The prognostic value of tissue-type plasminogen activator (tPA) measured in samples derived from 865 patients with primary breast cancer using a recently developed enzyme-linked immunosorbent assay (ELISA) was evaluated. Since the assay could easily
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c53baa4a76cea05cbdf5ac7b8cb1dd60
https://hdl.handle.net/2066/184848
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3
Cathepsin-D in primary breast cancer: prognostic evaluation involving 2810 patients
Autor: Maxime P. Look, J.A. Foekens, J Bolt-de Vries, W. L. J. Van Putten, J.G.M. Klijn, M.E. Meijer-van Gelder
Publikováno v: British Journal of Cancer
There is controversy regarding the prognostic value of cathepsin-D in primary breast cancer. An increased level of cathepsin-D in tumour extracts has been found to be associated with a poor relapse-free and overall survival. Studies performed with im
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ce9c935d220785d7ff0956286e5f1d
https://doi.org/10.1038/sj.bjc.6690048
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4
Effect of testosterone deprivation on expression of the androgen receptor in rat prostate, epididymis and testis
Autor: J. A. Grootegoed, J. Bolt-de Vries, J. M. S. Bartlett, Gerhard F. Weinbauer, Albert O. Brinkmann, Leen J. Blok, Eberhard Nieschlag, A. P. N. Themmen
Publikováno v: International Journal of Andrology. 15:182-198
Adult rats were treated with ethane dimethane sulphonate (EDS) to eliminate the Leydig cells. This treatment resulted in very low levels of testosterone in the blood and in the testis. Furthermore, histological evaluation of spermatogenesis showed no
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c07fb35d64a57517b0028d0ec9e9bc
https://doi.org/10.1111/j.1365-2605.1992.tb01125.x
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5
Androgens and androgen-receptors in prostate tissue from patients with benign prostatic hyperplasia: Effects of cyproterone acetate
Autor: P. J. Reuvers, J. Bolt-de Vries, Eppo Mulder, Fritz H. Schroeder, J. H. M. Blom, F. H. De Jong
Publikováno v: The Journal of Steroid Biochemistry and Molecular Biology. 42:49-55
Testosterone, 5 alpha-dihydrotestosterone and cyproterone acetate (CPA) were estimated in samples of prostate tissue, obtained from benign prostatic hyperplasia (BPH) patients who were or were not pretreated with CPA. Furthermore, these steroids were
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43dcf647a0ebe3c2107c4ecaab7dbf90
https://doi.org/10.1016/0960-0760(92)90010-g
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6
Androgen receptor heterogeneity and phosphorylation in human LNCaP cells
Autor: J.H. van Laar, J. Bolt-de Vries, Albert O. Brinkmann, N.D. Zegers, Jan Trapman
Publikováno v: Biochemical and Biophysical Research Communications. 166:193-200
Androgen receptor heterogeneity and phosphorylation were studied in the human LNCaP cell line. Fluorography after photoaffinity labeling as well as immunoblotting with a specific polyclonal antibody revealed that the human androgen receptor migrated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d757266927e896b109d51ac660796a9a
https://doi.org/10.1016/0006-291x(90)91930-q
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7
Abstract P3-02-05: Evaluation of Gene Transcripts in Primary Tumors at Time of Diagnosis and Circulating Tumor Cells (CTCs) at Time of Metastatic Disease
Autor: Bianca Mostert, Jack X. Yu, Jwm Martens, J Bolt-de Vries, P. van der Spoel, L.Y. Dirix, Yixin Wang, A van Galen, J.A. Foekens, Pa van Dam, Raquel Ramírez-Moreno, AM Sieuwerts, Stefan Sleijfer, Jan-Willem Gratama, Jan Kraan
Publikováno v: Cancer Research. 70:P3-02
Introduction: The enumeration of CTCs has already shown to bear clinical relevance as a prognostic and predictive factor in metastatic breast cancer. In addition to enumeration, isolation of CTCs enables their molecular characterization and thus hold
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::952ce6dc93d251149d889efd0757c921
https://doi.org/10.1158/0008-5472.sabcs10-p3-02-05
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9
The human androgen receptor is a 110 kDa protein
Autor: Albert O. Brinkmann, M.M. Voorhorst-Ogink, J.H. van Laar, J. Bolt-de Vries
Publikováno v: Molecular and Cellular Endocrinology. 63:39-44
The androgen receptor in human prostate carcinoma cells (LNCaP) has been studied after in situ photolabeling with [3H]R1881. Sodium dodecylsulfate-polyacrylamide gel electrophoresis (SDS-PAGE) analysis of whole cell extracts revealed the presence of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878ce958771b5a1e5db3cfc2ddcd5cb4
https://doi.org/10.1016/0303-7207(89)90079-8
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10
Prediction of time to progression after orchiectomy by the nuclear androgen receptor content from multiple biopsy specimens in patients with advanced prostate cancer
Autor: J. Bolt-de Vries, Marinus A. Blankenstein, Fritz H. Schröder, O. G. J. M. van Aubel
Publikováno v: The Prostate. 12:191-198
The nuclear androgen receptor (ARn) content of cancerous prostatic tissue has been investigated as a prognosticator for time to progression under endocrine therapy. In 1981 a prospective study was started to investigate whether the ARn content in bio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4183ae128ec718341f7b003ce1466cf5
https://doi.org/10.1002/pros.2990120302
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