Zobrazeno 1 - 10
of 519
pro vyhledávání: '"J Bissler"'
Publikováno v:
Brazilian Journal of Nephrology, Vol 46, Iss 3 (2024)
Abstract Tuberous sclerosis complex (TSC) is an autosomal dominant disease characterized by the development of hamartomas in the central nervous system, heart, skin, lungs, and kidneys and other manifestations including seizures, cortical tubers, rad
Externí odkaz:
https://doaj.org/article/14fb630815e949d59e576ade54b0b873
Autor:
Prashant Kumar, Fahad Zadjali, Ying Yao, Daniel Johnson, Brian Siroky, Aristotelis Astrinidis, Peter Vogel, Kenneth W. Gross, John J. Bissler
Publikováno v:
Genes and Diseases, Vol 9, Iss 1, Pp 187-200 (2022)
TSC renal cystic disease is poorly understood and has no approved treatment. In a new principal cell-targeted murine model of Tsc cystic disease, the renal cystic epithelium is mostly composed of type A intercalated cells with an intact Tsc2 gene con
Externí odkaz:
https://doaj.org/article/e9af695b73a243cab858e93e553b7277
Publikováno v:
Biology, Vol 12, Iss 9, p 1178 (2023)
Extracellular vesicles (EVs) are lipid membrane bound-cell-derived structures that are a key player in intercellular communication and facilitate numerous cellular functions such as tumor growth, metastasis, immunosuppression, and angiogenesis. They
Externí odkaz:
https://doaj.org/article/d46f74bf38a043d5a68cf59dd3aa47d2
Autor:
Stéphane Auvin, John J. Bissler, Vincent Cottin, Ayataka Fujimoto, Günther F. L. Hofbauer, Anna C. Jansen, Sergiusz Jóźwiak, Larissa Kerecuk, J. Christopher Kingswood, Romina Moavero, Roser Torra, Vicente Villanueva
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-10 (2019)
Abstract Background Tuberous sclerosis complex (TSC) is a rare autosomal dominant genetic disorder associated with mutations in TSC1 and TSC2 genes, upregulation of mammalian target of rapamycin signaling, and subsequent tumor formation in various or
Externí odkaz:
https://doaj.org/article/5860f640003143889943eadb4c9b82dc
Autor:
Prashant Kumar, Fahad Zadjali, Ying Yao, Brian Siroky, Aristotelis Astrinidis, Kenneth W. Gross, John J. Bissler
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
In tuberous sclerosis complex (TSC), Tsc2 mutations are associated with more severe disease manifestations than Tsc1 mutations and the role of extracellular vesicles (EVs) in this context is not yet studied. We report a comparative analysis of EVs de
Externí odkaz:
https://doaj.org/article/cfd84fb97743434386200feaede95852
Autor:
Prashant Kumar, Fahad Zadjali, Ying Yao, Michael Köttgen, Alexis Hofherr, Kenneth W. Gross, Darshan Mehta, John J. Bissler
Publikováno v:
Biology, Vol 11, Iss 5, p 709 (2022)
Patients with autosomal dominant polycystic kidney disease (ADPKD) and tuberous sclerosis complex (TSC) are born with normal or near-normal kidneys that later develop cysts and prematurely lose function. Both renal cystic diseases appear to be mediat
Externí odkaz:
https://doaj.org/article/1dbb8840bd5444d7bdfb49117c6c5786
Akademický článek
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Publikováno v:
Electroanalysis. 34:1587-1597
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9e7c461915332e651a0a3cf416dbdd9
https://doi.org/10.1002/elan.202100678
https://doi.org/10.1002/elan.202100678
Autor:
Aristotelis Astrinidis, John J. Bissler, Ying Yao, Fahad Zadjali, Daniel L. Johnson, Prashant Kumar, Kenneth W. Gross, Peter Vogel, Brian Siroky
Publikováno v:
Genes and Diseases, Vol 9, Iss 1, Pp 187-200 (2022)
Genes & Diseases
Genes & Diseases
TSC renal cystic disease is poorly understood and has no approved treatment. In a new principal cell-targeted murine model of Tsc cystic disease, the renal cystic epithelium is mostly composed of type A intercalated cells with an intact Tsc2 gene con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30778696e06d508bbfe267757da40013
https://doi.org/10.1016/j.gendis.2021.03.010
https://doi.org/10.1016/j.gendis.2021.03.010
Publikováno v:
Critical Reviews™ in Oncogenesis. 27:35-49
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder that affects both fetal development and postnatal tissue growth, resulting in altered brain structures and a tumor predisposition syndrome. Although every organ system is affected by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63b2bd67b6550ae8ca7ca379b33c806a
https://doi.org/10.1615/critrevoncog.2022042857
https://doi.org/10.1615/critrevoncog.2022042857