Zobrazeno 1 - 10
of 105
pro vyhledávání: '"J Bewick"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 8, Pp 2441-2445 (2019)
In flowering plants, gene body methylation (gbM) is associated with a subset of constitutively expressed genes. It has been proposed that gbM modulates gene expression. Here, we show that there are no consistent and direct differences to expression f
Externí odkaz:
https://doaj.org/article/a65bc7b0aa074f739d7fcccb6d86257e
Autor:
Adam J. Bewick, Zachary Sanchez, Elizabeth C. Mckinney, Allen J. Moore, Patricia J. Moore, Robert J. Schmitz
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-14 (2019)
Abstract Background The function of cytosine (DNA) methylation in insects remains inconclusive due to a lack of mutant and/or genetic studies. Results Here, we provide evidence for the functional role of the maintenance DNA methyltransferase 1 (Dnmt1
Externí odkaz:
https://doaj.org/article/7caff9abaf324f2fbb8973265459a04d
Publikováno v:
Tropical Doctor. 53:288-290
Laryngeal injury is rare but has a very high mortality rate. Compared to adults, laryngeal injury in children is more uncommon due to both behavioural and anatomical reasons. Severe laryngeal injury may require surgical repair, intensive care support
Autor:
Adam J. Bewick, Chad E. Niederhuth, Lexiang Ji, Nicholas A. Rohr, Patrick T. Griffin, Jim Leebens-Mack, Robert J. Schmitz
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-13 (2017)
Abstract Background The evolution of gene body methylation (gbM), its origins, and its functional consequences are poorly understood. By pairing the largest collection of transcriptomes (>1000) and methylomes (77) across Viridiplantae, we provide nov
Externí odkaz:
https://doaj.org/article/d5f095cbeff041e492681551754bf45e
Autor:
Adam J. Bewick, Brigitte T. Hofmeister, Kevin Lee, Xiaoyu Zhang, David W. Hall, Robert J. Schmitz
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 2, Pp 447-452 (2016)
We describe a suite of predictive models, coined FASTmC, for nonreference, cost-effective exploration and comparative analysis of context-specific DNA methylation levels. Accurate estimations of true DNA methylation levels can be obtained from as few
Externí odkaz:
https://doaj.org/article/23a71bf1b4984e6788a5ae7fb3f1f69a
Autor:
Timothy R Fallon, Sarah E Lower, Ching-Ho Chang, Manabu Bessho-Uehara, Gavin J Martin, Adam J Bewick, Megan Behringer, Humberto J Debat, Isaac Wong, John C Day, Anton Suvorov, Christian J Silva, Kathrin F Stanger-Hall, David W Hall, Robert J Schmitz, David R Nelson, Sara M Lewis, Shuji Shigenobu, Seth M Bybee, Amanda M Larracuente, Yuichi Oba, Jing-Ke Weng
Publikováno v:
eLife, Vol 7 (2018)
Fireflies and their luminous courtships have inspired centuries of scientific study. Today firefly luciferase is widely used in biotechnology, but the evolutionary origin of bioluminescence within beetles remains unclear. To shed light on this long-s
Externí odkaz:
https://doaj.org/article/8d5df25528e64fff99bdeaf0165f6fff
Autor:
Thomas J. S. Merritt, Adam J. Bewick
Publikováno v:
Frontiers in Genetics, Vol 8 (2017)
Insects encounter a variety of metals in their environment, many of which are required at some concentration for normal organismal homeostasis, but essentially all of which are toxic at higher concentrations. Insects have evolved a variety of genetic
Externí odkaz:
https://doaj.org/article/6f38f3375e9c4846b351c07ab317c945
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0182289 (2017)
Gene coexpression networks are a useful tool for summarizing transcriptomic data and providing insight into patterns of gene regulation in a variety of species. Though there has been considerable interest in studying the evolution of network topology
Externí odkaz:
https://doaj.org/article/b3f0fe6ed7364ec99cde23af369c0459
Autor:
Karolina Susek, Agnieszka Braszewska-Zalewska, Adam J Bewick, Robert Hasterok, Robert J Schmitz, Barbara Naganowska
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179821 (2017)
Deciphering the various chemical modifications of both DNA and the histone compound of chromatin not only leads to a better understanding of the genome-wide organisation of epigenetic landmarks and their impact on gene expression but may also provide
Externí odkaz:
https://doaj.org/article/ceac2a95452c405aadd7089be7d1fcca
Autor:
Victoria J. Bewick, Rebecca J. Mersh
Publikováno v:
Anaesthesia & Intensive Care Medicine. 21:630-633