Zobrazeno 1 - 10 of 280 pro vyhledávání: '"J Baro"'
1
Akademický článek
SUMOylation of the Kv4.2 Ternary Complex Increases Surface Expression and Current Amplitude by Reducing Internalization in HEK 293 Cells
Autor: Meghyn A. Welch, Leslie-Anne R. Jansen, Deborah J. Baro
Publikováno v: Frontiers in Molecular Neuroscience, Vol 14 (2021)
Kv4 α-subunits exist as ternary complexes (TC) with potassium channel interacting proteins (KChIP) and dipeptidyl peptidase-like proteins (DPLP); multiple ancillary proteins also interact with the α-subunits throughout the channel’s lifetime. Dyn
Externí odkaz: https://doaj.org/article/67944c3210c9430cae38053e7423d65b
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2
Akademický článek
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5
Akademický článek
Tonic 5nM DA stabilizes neuronal output by enabling bidirectional activity-dependent regulation of the hyperpolarization activated current via PKA and calcineurin.
Autor: Wulf-Dieter C Krenz, Edmund W Rodgers, Deborah J Baro
Publikováno v: PLoS ONE, Vol 10, Iss 2, p e0117965 (2015)
Volume transmission results in phasic and tonic modulatory signals. The actions of tonic dopamine (DA) at type 1 DA receptors (D1Rs) are largely undefined. Here we show that tonic 5nM DA acts at D1Rs to stabilize neuronal output over minutes by enabl
Externí odkaz: https://doaj.org/article/1192747609b74375838c3e77d73689b4
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6
Changes in peripheral HCN2 channels during persistent inflammation
Autor: Deborah J. Baro, X. L. Smith, Anne Z. Murphy, Lori A. Forster, Myurajan Rubaharan, L-A. R. Jansen
Publikováno v: Channels
article-version (VoR) Version of Record
Nociceptor sensitization following nerve injury or inflammation leads to chronic pain. An increase in the nociceptor hyperpolarization-activated current, Ih, is observed in many models of pathological pain. Pharmacological blockade of Ih prevents the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de30860c177a4518871900d69f281795
https://pubmed.ncbi.nlm.nih.gov/33423595
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7
Damage assessment and survival estimates in the wedge clam (Donax trunculus) caught by mechanical dredging in the northern Alboran Sea
Autor: Javier Urra, J. Baro, Tamara García, Pablo Marina
Publikováno v: e-IEO. Repositorio Institucional Digital de Acceso Abierto del Instituto Español de Oceanografía
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This paper describes the impact of dredging on populations of the wedge clam (Donax trunculus) at two sites along the northern Alboran coast. Damage was assessed by quantifying shell and foot damage on commercial clams caught with mechanical dredges.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85dd1d36c9b4ad4952c56f53683bcf20
http://hdl.handle.net/10508/11840
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8
Alterations in SUMOylation of the hyperpolarization-activated cyclic nucleotide-gated ion channel 2 during persistent inflammation
Autor: Leslie-Anne R. Jansen, Myurajan Rubaharan, Deborah J. Baro, Lori A. Forster, Anne Z. Murphy
Publikováno v: European Journal of Pain (London, England)
Background Unilateral injection of Complete Freund's Adjuvant (CFA) into the intra-plantar surface of the rodent hindpaw elicits chronic inflammation and hyperalgesia in the ipsilateral hindlimb. Mechanisms contributing to this hyperalgesia may act o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8096b924c7c6f51cf00c98a58d4fe9d7
https://pubmed.ncbi.nlm.nih.gov/32446289
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9
SUMOylating Two Distinct Sites on the A-type Potassium Channel, Kv4.2, Increases Surface Expression and Decreases Current Amplitude
Autor: Meghyn A. Welch, Lori A. Forster, Selin I. Atlas, Deborah J. Baro
Publikováno v: Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Post-translational conjugation of Small Ubiquitin-like Modifier (SUMO) peptides to lysine (K) residues on target proteins alters their interactions. SUMOylation of a target protein can either promote its interaction with other proteins that possess S
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a738f4aea61ad70135e9946dc50bbe
http://europepmc.org/articles/PMC6554448
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10
Modulator-Gated, SUMOylation-Mediated, Activity-Dependent Regulation of Ionic Current Densities Contributes to Short-Term Activity Homeostasis
Autor: Deborah J. Baro, Anna R. Parker, Lori A. Forster
Neurons operate within defined activity limits, and feedback control mechanisms dynamically tune ionic currents to maintain this optimal range. This study describes a novel, rapid feedback mechanism that uses SUMOylation to continuously adjust ionic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f683d153c09692f2a3ab13dde2566afb
https://europepmc.org/articles/PMC6343643/
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