Výsledky vyhledávání

An investigation of a possible role for mitochondrial nuclease in apoptosis

Autor: X W, Meng, M J, Fraser, C M, Ireland, J M, Feller, J B, Ziegler

Publikováno v: Apoptosis : an international journal on programmed cell death. 3(6)

Since mitochondrial factors have been implicated in apoptosis, experiments were designed to assess whether or not the potent mitochondrial nuclease could be one of these factors. Nuclei isolated by two different methods were found to contain mitochon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::875ff09acb24d7f6c8fcafda3a0e0485
https://pubmed.ncbi.nlm.nih.gov/14646472

Zobrazit plný text záznamu

Reduced memory B-cell populations in boys with B-cell dysfunction after bone marrow transplantation for X-linked severe combined immunodeficiency

Autor: S S, Ting, S G, Tangye, J, Wood, R A, Ffrench, J B, Ziegler

Publikováno v: British journal of haematology. 112(4)

X-linked severe combined immunodeficiency (XSCID) is a lethal disease resulting in death in infancy. In many instances, haploidentical bone marrow transplantation (BMT) offers reconstitution of T-cell immunity alone, with residual hypogammaglobulinae

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0db46481ab72f1e0394fa3f6ea442e80
https://pubmed.ncbi.nlm.nih.gov/11298599

Zobrazit plný text záznamu

Caspase-3-dependent and caspase-3-independent pathways leading to chromatin DNA fragmentation in HL-60 cells

Autor: X W, Meng, M J, Fraser, J M, Feller, J B, Ziegler

Publikováno v: Apoptosis : an international journal on programmed cell death. 5(1)

Apoptosis induced by etoposide (VP-16) in HL-60 cells was confirmed to be caspase-dependent. It was fully inhibited by the broad-spectrum caspase inhibitor Z-VAD-fmk. However, the caspase-3-specific inhibitor Z-DEVDfmk only partially inhibited apopto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::231d87e091c06218b42a165ca5123ca3
https://pubmed.ncbi.nlm.nih.gov/11227493

Zobrazit plný text záznamu

Caspase-3 activates endo-exonuclease: further evidence for a role of the nuclease in apoptosis

Autor: X W, Meng, M J, Fraser, J M, Feller, J B, Ziegler

Publikováno v: Apoptosis : an international journal on programmed cell death. 5(3)

Single-strand DNase and poly rAase, activities characteristic of endo-exonuclease, were co-activated in nuclear fractions of HL-60 cells by caspase-3. Activation was accompanied by cleavages of large soluble polypeptides (130-185 kDa) and a 65 kDa in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7d6b1bbfcdcc7bf36558d6c9279d4162
https://pubmed.ncbi.nlm.nih.gov/11225846

Zobrazit plný text záznamu

Identification of X-linked severe combined immunodeficiency by mutation analysis of blood and hair roots

Autor: S S, Ting, D, Leigh, R, Lindeman, J B, Ziegler

Publikováno v: British journal of haematology. 106(1)

Severe combined immunodeficiency is a heterogenous syndrome of varied genetic origins of which the X-linked type is the commonest (XSCID). The most sensitive method for diagnosis of XSCID in the absence of X-linked inheritance pattern is by mutation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dcaac01f32b3606594c8d3770e4a5bab
https://pubmed.ncbi.nlm.nih.gov/10444186

Zobrazit plný text záznamu

Successful bone marrow transplantation in a child with X-linked chronic granulomatous disease

Autor: C M, Ho, M R, Vowels, L, Lockwood, J B, Ziegler

Publikováno v: Bone marrow transplantation. 18(1)

A 16-month-old Aboriginal boy was diagnosed with chronic granulomatous disease (CGD) when he presented with frequent significant infections from the age of 12 months. BMT was performed from a HLA-matched sibling after conditioning with busulphan, cyc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::45886c69e081e807b270f6d7a6db6ce3
https://pubmed.ncbi.nlm.nih.gov/8832019

Zobrazit plný text záznamu

Managing HIV. Part 6: People living with HIV. 6.3 Children with HIV

Autor: J B, Ziegler, S, Blanche, R, Loh

Publikováno v: The Medical journal of Australia. 164(11)

Sometimes the diagnosis of HIV in a child is the first sign that other family members are affected by the virus. The immature immune system of children responds to HIV infection differently to that of adults. Disease progression is rapid in some, but

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::da66558f42e453c6146daca30a95739b
https://pubmed.ncbi.nlm.nih.gov/8657032

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání