Zobrazeno 1 - 10
of 93
pro vyhledávání: '"J B Weinberg"'
Publikováno v:
European Cells & Materials, Vol 13, Pp 56-65 (2007)
Molecular oxygen is required for the production of nitric oxide (NO), a pro-inflammatory mediator that is associated with osteoarthritis and rheumatoid arthritis. To date there has been little consideration of the role of oxygen tension in the regula
Externí odkaz:
https://doaj.org/article/503a61da75ab46a58b633593812f8b57
Publikováno v:
Osteoarthritis Cartilage
Injury to the meniscus is common and frequently leads to the development of post-traumatic osteoarthritis (PTOA). Many times meniscus injuries occur coincident with anterior cruciate ligament (ACL) injuries and lead to a bloody joint effusion. Hemart
Autor:
Matthew P. Rubach, Donald L. Granger, Esther D. Mwaikambo, Margaret A. Bush, Nicholas M. Anstey, Tsin W. Yeo, Youwei Chen, Salvatore M. Florence, J B Weinberg, Ayam R. Kalingonji
Publikováno v:
FASEB J
A layer of glycocalyx covers the vascular endothelium serving important protective and homeostatic functions. The objective of this study was to determine if breakdown of the endothelial glycocalyx (eGC) occurs during malaria infection in children. M
Publikováno v:
Journal of the Pediatric Infectious Diseases Society. 10:S12-S12
Background Candida species are the most common cause of fungal infection in hospitalized patients. Patients with candidemia are at risk of developing disseminated infection. Studies in adults have described risk factors for disseminated candidiasis i
Autor:
Jackson Mukemba, Hao Wang, Donald L. Granger, Alicia D. Volkheimer, Tsin W. Yeo, Esther D. Mwaikambo, Matthew P. Rubach, Youwei Chen, Salvatore M. Florence, Nicholas M. Anstey, J B Weinberg
Publikováno v:
The Journal of Infectious Diseases. 210:913-922
Falciparum malaria remains a significant problem worldwide causing over 0.6 million deaths yearly, mostly in children [1, 2]. New insights into malaria pathophysiology and new treatments are needed. Nitric oxide (NO) is important in resistance to sev
Publikováno v:
Blood Cancer Journal
Double IGHV DNA gene rearrangements in CLL: influence of mixed-mutated and -unmutated rearrangements on outcomes in CLL
Autor:
Christian Fink, Farshid Guilak, J B Weinberg, Mary A. Misukonis, Beverley Fermor, David S. Pisetsky
Publikováno v:
Osteoarthritis and Cartilage. 10:792-798
Objective Biomechanical signals play important roles in regulating the homeostasis of articular cartilage, but under abnormal conditions may be a critical factor in the onset and progression of arthritis. Prostaglandin E 2 (PGE 2 ) and nitric oxide (
Publikováno v:
Arthritis & Rheumatism. 42:569-573
Human interferon-alpha (IFNalpha) and IFNbeta are administered for treatment of several diseases, including viral infections, malignancies, and multiple sclerosis (MS). IFNalpha therapy has been associated with the production of autoantibodies and th
Autor:
J B Weinberg
Publikováno v:
Environmental Health Perspectives
Nitric oxide (.NO) may exhibit proinflammatory features. .NO synthase type 2 (NOS2) is overexpressed and .NO overproduced in rodent models of induced inflammation. Blockage of .NO production by administration of NOS inhibitors prevents or reduces var
Publikováno v:
The Journal of Experimental Medicine
Although researchers have noted high level activation of rodent mononuclear phagocytes for nitric oxide (NO) synthase type 2 (S2) expression and NO production with a variety of agents such as interferon (IFN) gamma and endotoxin, it has been difficul