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Autor:
Paul E. Aldrich, William A. Price, J V Duncia, J B Santella rd, Ruth R. Wexler, Michael E. Pierce, Gregory J. Wells, Andrew T. Chiu, David J. Carini, Alexander L. Johnson
Publikováno v:
Journal of Medicinal Chemistry. 34:2525-2547
A new series of nonpeptide angiotensin II (AII) receptor antagonists has been prepared. These N-(biphenylyl-methyl)imidazoles, e.g. 2-butyl-1-[(2'-carboxybiphenyl-4-yl)methyl]-4-chloro-5- (hydroxymethyl)imidazole, differ from the previously reported