Zobrazeno 1 - 10
of 36
pro vyhledávání: '"J B Glen"'
Publikováno v:
Anaesthesia. 69:429-435
Summary We studied the use of a new ke0 value (0.6 min−1) for the Marsh pharmacokinetic model for propofol. Speed of induction and side-effects produced were compared with three other target-controlled infusion systems. Eighty patients of ASA physi
Autor:
J. B. Glen, F. H. M. Engbers
Publikováno v:
Anaesthesia, 71(3), 306-314
One advantage of effect-site target-controlled infusion is the administration of a larger initial dose of propofol to speed up the induction of anaesthesia. This dose is determined by the combination of the pharmacokinetic model parameters, the targe
Publikováno v:
Anaesthesia, 69(5), 420-428
Summary Debate continues over the most appropriate blood–brain equilibration rate constant (ke0) for use with the Marsh pharmacokinetic model for propofol. We aimed to define the optimal ke0 value. Sixty-four patients were sedated with incremental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9d4b0088469388fa573e9c274f5153e
https://hdl.handle.net/1887/105894
https://hdl.handle.net/1887/105894
Publikováno v:
Veterinary Record. 148:198-203
The performance of a modified target-controlled infusion system was investigated in 16 dogs undergoing routine dental work, by comparing the predicted concentrations of propofol in venous blood samples with direct measurements; the optimum targets fo
Autor:
J. B. Glen
Publikováno v:
Anaesthesia. 53:13-21
The 'Diprifusor' target controlled infusion system has been developed as a standardised infusion system for the administration of propofol by target controlled infusion. A preferred set of pharmacokinetic parameters for propofol was selected using co
Publikováno v:
Anaesthesia. 53:61-67
The predictive performance of a 'Diprifusor' target controlled infusion system for propofol was examined in 46 patients undergoing major surgery, divided into three age groups (18-40, 41-55 and 56-80 years). Measured arterial propofol concentrations
Autor:
J. B. Glen, M. White
Publikováno v:
Anaesthesia, 69(6), 550-557. Wiley-Blackwell
Summary We compared the predictive performance of the existing Diprifusor and Schnider models, used for target-controlled infusion of propofol, with a new modification of the Diprifusor model (White) incorporating age and sex covariates. The bias and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e14cd0ef9ded63c095337d862c07b55
https://pure.amc.nl/en/publications/a-comparison-of-the-predictive-performance-of-three-pharmacokinetic-models-for-propofol-using-measured-values-obtained-during-targetcontrolled-infusion(1fe54def-a978-4961-8664-d5070d00e7b0).html
https://pure.amc.nl/en/publications/a-comparison-of-the-predictive-performance-of-three-pharmacokinetic-models-for-propofol-using-measured-values-obtained-during-targetcontrolled-infusion(1fe54def-a978-4961-8664-d5070d00e7b0).html
Publikováno v:
Anesthesiology. 82:1328-1345
Background Computer-assisted target controlled infusions (TCI) result in prediction errors that are influenced by pharmacokinetic variability among and within patients. It is uncertain whether the selection of a propofol pharmacokinetic parameter set
Publikováno v:
British Journal of Anaesthesia. 69:375-381
We have studied the effects of graded infusion rates of propofol (0.2-0.5 mg kg-1 min-1) on left ventricular global and regional function, in eight acutely instrumented dogs. Global function was assessed by measurement of aortic and left ventricular
Publikováno v:
Anaesthesia. 64(1)
The utility of two-choice visual reaction time testing using a specially programmed mobile telephone as a measure of sedation level was investigated in 20 healthy patients sedated with target controlled infusions of propofol. At gradually increasing