Zobrazeno 1 - 10
of 97
pro vyhledávání: '"J B Fourtillan"'
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 280:E11-E22
The magnitude and duration of melatonin (MLT) secretion were measured over a period of 25 h with pharmacokinetic studies employing administration of D7MLT at midday and at midnight in two separate studies and two groups of subjects, 12 young and 11 o
Publikováno v:
Biopharmaceutics & Drug Disposition. 21:15-22
Absolute bioavailability of the neurohormone melatonin (MLT) was studied in 12 young healthy volunteers (six males, six females) after administration at midday, on two separate occasions, of 23 microg by intravenous (i.v.) infusion and 250 microg by
Publikováno v:
Biological Mass Spectrometry. 23:581-589
A new sensitive assay has been developed for the quantitative measurement of BN50727 at the picomole level in human plasma and urine. The drug and the internal standard (BN50788) were measured by combined liquid chromatography/negative ion chemical i
Publikováno v:
Chromatographia. 39:228-238
A simple and sensitive assay has been developed for the quantitative measurement of a new platelet activating factor antagonist (BN50730), and its two main metabolites (BN50727 and BN50922), at the picomole level in human plasma and urine. The three
Publikováno v:
Current Therapeutic Research. 55:569-575
The pharmacokinetics of both ampicillin and sulbactam obtained from a balanced, open, two-way crossover study in 20 young healthy volunteers receiving a single 375-mg oral tablet of sultamicillin administered as two different formulations were compar
Publikováno v:
Biological Mass Spectrometry. 22:395-402
A highly sensitive and specific assay was developed for the quantitative measurement of 4-hydroxy tamoxifen (4-OH Tam) at the femtomole level in human plasma and mammary tumours. The drug and deuterated internal standard (4-OH Tam D4) were measured b
Publikováno v:
The Journal of Clinical Pharmacology. 33:480-485
The pharmacokinetic and safety profiles of clarithromycin (C) and its 14-hydroxy-clarithromycin (HC) metabolite were determined after a multiple-dose oral clarithromycin regimen (250 mg twice daily for five doses) in six healthy subjects and seven pa
Autor:
J. B. Fourtillan, J. Girault
Publikováno v:
Drug Investigation. 4:435-440
The pharmacokinetic parameters of a piroxicam 0.5% topical gel were determined in 20 healthy volunteers (6 women and 14 men) following application of multiple doses (20mg piroxicam daily) over 14 days. 21 blood samples were drawn from each patient be
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 564:43-53
A new simple and sensitive assay has been developed for the simultaneous quantitative measurement of beclomethasone dipropionate and its hydrolysis products in human plasma and urine. Beclomethasone 17.21-dipropionate, beclomethasone 17-monopropionat
Publikováno v:
British Journal of Clinical Pharmacology. 30:616-620
Pharmacokinetic interaction between ponsinomycin-nicoumalone was studied in six subjects who received an 8 mg oral dose of racemic nicoumalone alone and 4 days into an oral regimen of ponsinomycin 800 mg twice daily. The concentrations of R(+) and S(