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Autor:
S M Cowell, C L Becker, M M Javadpour, J B Alberty, M L McLaughlin, M M Juban, W C Lo, S M Bishop
Publikováno v:
Journal of Medicinal Chemistry. 39:3107-3113
De novo antimicrobial peptides with the sequences: (KLAKKLA)n, (KLAKLAK)n (where n = 1,2,3), (KALKALK)3, (KLGKKLG)n, and (KAAKKAA)n (where n = 2,3), were prepared as the C-terminus amides. These peptides were designed to be perfectly amphipathic in h