Zobrazeno 1 - 10
of 21
pro vyhledávání: '"J B, Zeldis"'
Publikováno v:
Current Medical Research and Opinion. 24:1529-1538
To evaluate the clinical and biological activity of apremilast in patients with severe plaque-type psoriasis.Apremilast, a phosphodiesterase-4 inhibitor, inhibits in vitro activity of multiple inflammatory factors implicated in the pathogenesis of ps
Autor:
J C, Mansfield, M, Parkes, A B, Hawthorne, A, Forbes, C S J, Probert, R C, Perowne, A, Cooper, J B, Zeldis, D C, Manning, C J, Hawkey
Publikováno v:
Alimentary pharmacologytherapeutics. 26(3)
Therapy targeted at tumour necrosis factor-alpha has an established role in Crohn's disease. Lenalidomide, an analogue of thalidomide, is an oral immunomodulatory agent with powerful antitumour necrosis factor-alpha properties. It is licensed for mye
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(11)
We investigated the effect of thalidomide, a compound with immunomodulatory and antiangiogenic properties, on lipopolysaccharide (LPS)-mediated induction of cyclooxygenase-2 (Cox-2) and prostaglandin (PG) biosynthesis in murine macrophages. Thalidomi
Publikováno v:
The American journal of gastroenterology. 93(4)
We evaluated the efficacy and safety of a twice-daily dosage regimen of cisapride 20 mg in relieving the symptoms of mild-moderate gastroesophageal reflux disease (GERD) in patients with moderate intensity heartburn and no history of erosive esophagi
Publikováno v:
The American journal of managed care. 3(12)
Identification of inefficiencies is a first step to improving the quality of gastrointestinal (GI) care at the most reasonable cost. This analysis used administrative data to examine the healthcare utilization and associated costs of the management o
Publikováno v:
The Journal of infectious diseases. 174(4)
Hepatitis C virus (HCV) has been detected in peripheral blood mononuclear cells (PBMC) from persons chronically infected with HCV. Reports describe altered monocytic function during HCV infection; however, the immunologic consequences of HCV tropism
Publikováno v:
Biotechnology and applied biochemistry. 23(3)
Plasmid DNA condensed by polylysine enhanced cationic-liposome-mediated transfection of Hep G2 cells. The luciferase expression plasmid pCMVL was complexed with the polycation poly-L-lysine and mixed with liposomes that contained a 1:1 molar ratio of
Publikováno v:
Annals of Saudi medicine. 15(5)
Publikováno v:
Hepatology (Baltimore, Md.). 18(5)
Peripheral blood mononuclear cell proliferative responses in vitro to recombinant yeast or Escherichia coli hepatitis C virus fusion proteins were evaluated in 20 patients with chronic hepatitis C who were reactive for antibody to hepatitis C virus (
Autor:
P H, Hayashi, J B, Zeldis
Publikováno v:
Comprehensive therapy. 19(5)
Five viruses are the major causes of hepatitis. These viruses are totally unrelated to each other in structure and mode of replication despite the similarity in the acute syndrome produced by each virus. HAV is a single-stranded RNA virus that has a