Zobrazeno 1 - 10
of 54
pro vyhledávání: '"J B, Richards"'
Autor:
Martin I. Jones, Joseph D. Szustakowski, Giorgio Sirugo, Lukas Habegger, Adam J. Mansfield, Will Salerno, Joshua D. Backman, Athanasios Kousathanas, David J. Carey, Yi-Pin Lai, James F. Wilson, Alison M. Meynert, Anne E. Justice, Alexander H. Li, Jack A. Kosmicki, Anthony Marcketta, Sándor Szalma, Shane McCarthy, A. R. Shuldiner, A. Baras, Daniel J. Rader, Michael N. Cantor, Ashish Yadav, Manuel A. R. Ferreira, F. S. P. Kury, Konrad Rawlik, Loukas Moutsianas, Gonçalo R. Abecasis, Susan P. Walker, Xing Chen, Albert Tenesa, Paul Nioi, Adam E. Locke, Guillaume Butler-Laporte, E. N. Smith, Richard H Scott, Gundula Povysil, Joseph B. Leader, Lauren Gurski, Dorota Pasko, Marylyn D. Ritchie, A. Cordova-Palomera, Kyoko Watanabe, Colm O'Dushlaine, A. O'Neill, Tomoko Nakanishi, Erola Pairo-Castineira, Xiuwen Zheng, Emily Wong, Jeffrey G. Reid, Slavé Petrovski, Julie E. Horowitz, Anurag Verma, Justin W. Davis, Dylan Sun, Sahar Esmaeeli, Heiko Runz, Quanli Wang, John D. Overton, Shareef Khalid, Tooraj Mirshahi, Evan Maxwell, Mark J. Caulfield, Mark Lathrop, Olympe Chazara, Deepika Sharma, David Goldstein, Jonathan Marchini, Xiaodong Bai, Suganthi Balasubramanian, Krzysztof Kiryluk, Nilanjana Banerjee, Rouel Lanche, J. B. Richards, Hyun Min Kang, J. K. Baillie, Yunfeng Huang, Sean O'Keeffe, Erika Kvikstad, Margaret M. Parker, Joelle Mbatchou
Publikováno v:
American Journal of Human Genetics
2021, ' Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals ', American Journal of Human Genetics . https://doi.org/10.1016/j.ajhg.2021.05.017
2021, ' Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals ', American Journal of Human Genetics . https://doi.org/10.1016/j.ajhg.2021.05.017
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), a respiratory illness that can result in hospitalization or death. We used exome sequence data to investigate associations between rare genetic v
Publikováno v:
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.
Objective The effect of body mass index (BMI) on the risk of infectious diseases admissions and mortality is unclear and is difficult to study given the risks of confounding variables. Methods We used genome-wide association studies (GWASs) with mend
Autor:
Lewis, J. B. Richards
Publikováno v:
The British Medical Journal, 1958 Apr . 1(5076), 944-944.
Externí odkaz:
https://www.jstor.org/stable/25380332
Autor:
Kathleen A. Jablonski, Tim D. Spector, Paul W. Franks, Toni I. Pollin, William C. Knowler, Jose C. Florez, J. B. Richards, Dawn M. Waterworth, F. X. Pi-Sunyer, Tohru Funahashi, Steven E. Kahn, Costas A. Christophi, Kieren J. Mather, Zari Dastani, Ronald B. Goldberg
Publikováno v:
Diabetic Medicine. 29:1579-1588
Aims Baseline adiponectin concentrations predict incident Type 2 diabetes mellitus in the Diabetes Prevention Program. We tested the hypothesis that common variants in the genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1, ADIPOR2) would
Autor:
J. B. Richards, Ian R. Reid
Publikováno v:
Clinical Reviews in Bone and Mineral Metabolism. 7:240-248
The adipocyte is an important source of factors that act as circulating regulators of bone metabolism. These include estrogens, and the adipokines, leptin, resistin, adiponectin, and probably others. Leptin acts directly on bone cells, and in some ex
Autor:
Abraham Aviv, Massimo Mangino, Nilesh J. Samani, Nicole Soranzo, Tim D. Spector, Guangju Zhai, Ana M. Valdes, J. B. Richards, Panagiotis Deloukas
Publikováno v:
Journal of Medical Genetics
Journal of Medical Genetics, BMJ Publishing Group, 2009, 46 (7), pp.451. ⟨10.1136/jmg.2008.064956⟩
Journal of Medical Genetics, BMJ Publishing Group, 2009, 46 (7), pp.451. ⟨10.1136/jmg.2008.064956⟩
Background: Telomere length is a predictor for a number of common age related diseases and is a heritable trait. Methods and results: To identify new loci associated with mean leukocyte telomere length we conducted a genome wide association study of
Autor:
Paula M L Skidmore, Jane Skinner, Aedin Cassidy, J. B. Richards, Alex J. MacGregor, Keith Burling, Ailsa A Welch, Eric B. Rimm, Susan J. Fairweather-Tait, Tim D. Spector
Publikováno v:
The Journal of Nutrition. 139:353-358
Circulating adiponectin is emerging as an important link between obesity, type 2 diabetes, and cardiovascular disease (CVD). However, the spectrum of lifestyle factors that modulate the adiponectin concentration remains to be elucidated, particularly
Autor:
Abraham Aviv, A. Siva, Morris J. Brown, Masayuki Kimura, J. B. Richards, Tim D. Spector, Xiaobin Lu, J. P. Gardner, Bernet S. Kato, Ana M. Valdes
Publikováno v:
Atherosclerosis. 200:271-277
Objective Elevated plasma homocysteine is a risk factor for vascular diseases, possibly due to homocysteine-mediated increase in oxidative stress and inflammation. As leukocyte telomere length (LTL) registers the cumulative oxidative stress and infla
Autor:
Scott Wilson, Tim D. Spector, Mario Falchi, Gabriela L. Surdulescu, Suzanne J. Brown, Vijay Panicker, J. B. Richards, Ee Mun Lim, John P. Walsh, Stephen J. Fletcher
Publikováno v:
Clinical Endocrinology. 68:652-659
Objective Thyroid hormone action influences many metabolic and synthetic processes, but the degree of regulation attributed to genes and environmental factors affecting normal variation remains controversial. Design We investigated the magnitude of t
Autor:
Allan Hakim, Deborah J. Hart, J. B. Richards, Ana M. Valdes, Tim D. Spector, Guangju Zhai, Bernet S. Kato
Publikováno v:
Osteoporosis International. 19:1211-1217
In this 15-year follow-up study, we found that the estimated rate of bone loss at the femoral neck (FN) for women aged 45-68 was linear at a rate of 1.67% per year, but quadratic for lumbar spine (LS) at a rate of 3.12% initially, and slowing down wi