Zobrazeno 1 - 10
of 16
pro vyhledávání: '"J B, Monahan"'
Autor:
P R, Streeter, N I, Minster, L E, Kahn, W F, Hood, L E, Vickery, T L, Thurman, J B, Monahan, J K, Welply, J P, McKearn, S L, Woulfe
Publikováno v:
Experimental hematology. 29(1)
The progenipoietins, a class of engineered proteins containing both fetal liver tyrosine kinase-3 and granulocyte colony-stimulating factor receptor agonist activities, were functionally characterized in vitro and in vivo. Four representative progeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59df87c901e781be41d62c4fb19e2c8d
https://pubmed.ncbi.nlm.nih.gov/11164104
https://pubmed.ncbi.nlm.nih.gov/11164104
Autor:
R, Pellicciari, M, Marinozzi, B, Natalini, G, Costantino, D C, Lankin, J P, Snyder, J B, Monahan
Publikováno v:
Farmaco (Societa chimica italiana : 1989). 52(6-7)
Two new spirobicyclophosphonate isomers (19 and 20), conformationally constrained analogues of the potent competitive NMDA antagonist CGS 19755 (4), have been designed and synthetized with the aim of gaining insight into the conformational preference
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a98a50568c0ca1291751a65dbb60b59
https://pubmed.ncbi.nlm.nih.gov/9490080
https://pubmed.ncbi.nlm.nih.gov/9490080
Autor:
S J, Mnich, A W, Veenhuizen, J B, Monahan, K C, Sheehan, K R, Lynch, P C, Isakson, J P, Portanova
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 155(9)
We describe the generation of an IgG1 mAb, 2B5, that neutralizes the biologic activity of PGE2 in vitro and in vivo. The Ab was derived from a BALB/c mouse that was immunized with a PGE2-thyroglobulin conjugate. 2B5 is one of the highest affinity and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::917f7ec84a4d8ba528dec957cc72699d
https://pubmed.ncbi.nlm.nih.gov/7594605
https://pubmed.ncbi.nlm.nih.gov/7594605
Autor:
W F, Hood, N M, Gray, M S, Dappen, G B, Watson, R P, Compton, A A, Cordi, T H, Lanthorn, J B, Monahan
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 262(2)
We have synthesized a series of indole-2-carboxylate derivatives and, with the use of radioligand binding, electrophysiological techniques and an in vivo transient bilateral carotid occlusion model of ischemic damage known to be sensitive to NMDA ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b699f0b2d2ef938e3785d7c4c29fe60
https://pubmed.ncbi.nlm.nih.gov/1386886
https://pubmed.ncbi.nlm.nih.gov/1386886
Autor:
M L, Vazquez, D J, Garland, E T, Sun, J A, Cler, S J, Mick, W F, Hood, J B, Monahan, S, Iyengar, T S, Rao
Publikováno v:
Neuroscience letters. 135(2)
(+/-)-3-Carboxy-5-phosphono-1,2,3,4-tetrahydroisoquinoline (SC-48981), a conformationally restricted analog of the potent competitive N-methyl-D-aspartate (NMDA) antagonist, 2-amino-5-phosphonopentanoate (AP-5), potently inhibited the binding of [3H]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::598ffd35c7a9fea3f042b6282ddfd723
https://pubmed.ncbi.nlm.nih.gov/1352628
https://pubmed.ncbi.nlm.nih.gov/1352628
Autor:
R, Pellicciari, B, Natalini, M, Marinozzi, B M, Sadeghpour, A A, Cordi, T H, Lanthorn, W F, Hood, J B, Monahan
Publikováno v:
Farmaco (Societa chimica italiana : 1989). 46(11)
The four D-2-amino-4,5-methano-adipates 26, 27, 32, 33 were synthesized and their biological activity at the N-methyl-D-aspartate (NMDA) receptor was assessed. The synthesis involved as a key step a rhodium acetate dimer catalyzed addition of ethyl d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c33a40426650242170d3d31b466742c
https://pubmed.ncbi.nlm.nih.gov/1667358
https://pubmed.ncbi.nlm.nih.gov/1667358
Autor:
J B, Monahan, J P, Biesterfeldt, W F, Hood, R P, Compton, A A, Cordi, M I, Vazquez, T H, Lanthorn, P L, Wood
Publikováno v:
Molecular pharmacology. 37(6)
The competitive N-methyl-D-aspartate (NMDA) receptor antagonist D-2-amino-5-phosphonopentanoate and two other five-atom linkage (C-5) omega-phosphono-alpha-amino acid analogs reduced [3H]glycine binding, in a dose-dependent manner, to a maximum of 45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f79b25bbb1d46886a9055bd549dd245
https://pubmed.ncbi.nlm.nih.gov/2163012
https://pubmed.ncbi.nlm.nih.gov/2163012
Publikováno v:
Neuroscience letters. 112(2-3)
The 4 configurational isomers of D-3,4-cyclopropylglutamate (D-CGA) have been synthesized and analyzed for their interactions as excitatory amino acid recognition sites. Additionally, functional assessment of the action of these compounds at the N-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d39be62be9b2d5117aba1ea655ddfaaa
https://pubmed.ncbi.nlm.nih.gov/2163042
https://pubmed.ncbi.nlm.nih.gov/2163042
Publikováno v:
Journal of Biological Chemistry. 255:11997-12005
The eighth component of human complement (C8) has been purified in high yield from Cohn Fraction III and characterized with regard to its physicochemical properties and subunit structure. The purified product was found to be similar to functional C8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0412291a7fa4b9e627bfb2d5a5a4e25
https://doi.org/10.1016/s0021-9258(19)70233-6
https://doi.org/10.1016/s0021-9258(19)70233-6
Publikováno v:
Journal of Biological Chemistry. 258:5056-5062
The association of the eighth (C8) and ninth (C9) components of human complement within membrane-bound C5b-9 was investigated using the photosensitive cross-linking reagent N-succinimidyl-6-(4'-azido-2'-nitrophenylamino)hexanoate. Reaction of this re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90e663db72bbf5c5d1563aa7f52f0d2c
https://doi.org/10.1016/s0021-9258(18)32537-7
https://doi.org/10.1016/s0021-9258(18)32537-7