Zobrazeno 1 - 7
of 7
pro vyhledávání: '"J B, Meko"'
Publikováno v:
The Journal of Immunology. 158:3359-3365
Although IL-12 possesses the most potent single-cytokine antitumor efficacy, the mechanism by which IL-12 exerts its antitumor activities remains unclear. Using a complete tumor regression model induced by IL-12 treatment, we demonstrate that the ant
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(3)
Previous studies have demonstrated eradication of small (4-8 mm) established murine MCA207 sarcomas by treatment with systemic IL-12. Analysis of the mechanism has revealed a cellular and molecular immune response at the tumor typical of a Th1 cell-m
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 158(7)
Although IL-12 possesses the most potent single-cytokine antitumor efficacy, the mechanism by which IL-12 exerts its antitumor activities remains unclear. Using a complete tumor regression model induced by IL-12 treatment, we demonstrate that the ant
Autor:
G R, Peplinski, A K, Tsung, M J, Casey, J B, Meko, T N, Fredrickson, R M, Buller, J A, Norton
Publikováno v:
The cancer journal from Scientific American. 2(1)
This study investigates the feasibility of systemic gene delivery in a tumor-bearing host using a vaccinia virus-based in vivo gene delivery and expression system.A recombinant vaccinia virus encoding human interleukin-1beta (hIL-1beta) was construct
Publikováno v:
Cancer research. 55(21)
We have constructed a recombinant vaccinia virus (recVV), vKT0334 mIL-12, containing the genes encoding the p35 and p40 subunits of murine interleukin-12 (mIL-12). In vitro experiments demonstrated that vKT0334 mIL-12 efficiently infected a variety o
Autor:
J B Meko, J A Norton
Publikováno v:
The British journal of surgery. 81(7)
Autor:
J B, Meko, J A, Norton
Publikováno v:
Current opinion in general surgery.
Pancreatic endocrine tumors are rare, yet can cause significant morbidity due to excessive secretion of hormones. Octreotide is effective in reducing the plasma concentrations of many of these hormones. The availability of potent H2-receptor antagoni