Zobrazeno 1 - 10
of 53
pro vyhledávání: '"J B, McCarthy"'
Publikováno v:
The Journal of Immunology. 159:2424-2430
Leukocyte integrins are fundamentally important in modulating adhesion to extracellular matrix components and to other cells. This integrin-mediated adhesion controls leukocyte arrest and extravasation during the onset of inflammatory responses. More
Autor:
N L McCartney-Francis, D E Mizel, R S Redman, M Frazier-Jessen, R B Panek, A B Kulkarni, J M Ward, J B McCarthy, S M Wahl
Publikováno v:
The Journal of Immunology. 157:1306-1312
The targeted disruption of the TGF-beta1 gene in mice (TGF-beta1 -/-) leads to extensive inflammation in vital organs, cachexia, and death within 3 to 4 wk. Significant inflammatory lesions develop initially in the periductal regions of the salivary
Publikováno v:
The Journal of Immunology. 153:3440-3449
ELISA determinations revealed substantial concentrations (0.49 to 2.10 micrograms/ml) of soluble CD44 in murine serum, with some variation among normal mouse strains. At least three species of CD44 were identified by immunoprecipitation and SDS-PAGE
Publikováno v:
Blood. 84:1802-1811
Close interaction of human hematopoietic progenitors with the bone marrow microenvironment is important for the ordered progression of human hematopoiesis. Progenitor cell adhesion to stroma has a complex molecular basis, involving various cell-extra
Publikováno v:
Blood. 81:2272-2282
Self-renewal and differentiation of B-cell precursors is dependent on interactions with bone marrow (BM) stromal cells and associated extracellular matrix. We have recently developed an interleukin (IL)-7- dependent, BM-derived stromal cell culture t
Publikováno v:
Nature Neuroscience. 3:311-313
Publikováno v:
Journal of biomedical materials research. 50(1)
We report a new method to create a biofunctional surface in which the accessibility of a ligand is used as a means to influence the cell behavior. Supported bioactive bilayer membranes were created by Langmuir-Blodgett (LB) deposition of either a pur
Publikováno v:
Cancer. 86(11)
Recent reports have shown altered expression of CD44 in renal cell carcinomas. However, to the authors' knowledge there are no data correlating CD44 expression in renal cell carcinomas with subsequent tumor progression or recurrence, nor is there inf
Publikováno v:
Journal of neurochemistry. 70(5)
Neuropeptide Y (NPY) gene expression is known to be modulated in the mossy fiber projection of hippocampal granule cells following seizure. We investigated NPY biosynthesis and metabolism in an attempt to characterize NPY biochemically as a neurotran
Autor:
N L, McCartney-Francis, D E, Mizel, M, Frazier-Jessen, A B, Kulkarni, J B, McCarthy, S M, Wahl
Publikováno v:
The American journal of pathology. 151(5)
Mice homozygous for a nonfunctional transforming growth factor-beta 1 gene develop rampant inflammation in vital organs that contributes to a shortened life span. The presence of circulating anti-nuclear anti-bodies, immune deposits in tissues, leuko