Výsledky vyhledávání - "J B, Hamburger"

Multiple conformational states of a new hematopoietic cytokine (megakaryocyte growth and development factor): pH- and urea-induced denaturation

Autor: J B, Hamburger, E, Chen, L O, Narhi, G M, Wu, D N, Brems

Publikováno v: Proteins. 32(4)

The effect of pH and urea on the conformation of recombinant human megakaryocyte growth and development factor (rHuMGDF) was determined by circular dichroism, intrinsic fluorescence spectroscopy, and equilibrium ultracentrifugation. The conformation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f7604b22aee1c55118ec148c2221e37c
https://pubmed.ncbi.nlm.nih.gov/9726418

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Characterization and stability of N-terminally PEGylated rhG-CSF

Autor: O B, Kinstler, D N, Brems, S L, Lauren, A G, Paige, J B, Hamburger, M J, Treuheit

Publikováno v: Pharmaceutical research. 13(7)

The liquid stability of rhG-CSF was investigated after polyethylene glycol (PEG) with an average molecular weight of 6000 daltons was covalently attached to the N-terminal methionine residue.The conjugation methods chosen for modifying the N-terminal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f6bf22302bdb5a0aaaeee5030c3d1eaf
https://pubmed.ncbi.nlm.nih.gov/8842035

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