Zobrazeno 1 - 10
of 304
pro vyhledávání: '"J Arnt"'
Publikováno v:
Pharmacology Biochemistry and Behavior. 71:635-643
The 5-HT(6) receptor is targeted by several new antipsychotics such as clozapine, olanzapine, and sertindole. We studied the effect of SB-271046 [5-chloro-N-(4-methoxy-3-piperazin-1-yl-phenyl)-3-methyl-2-benzothiophenesulfonamide], a specific 5-HT(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690838b3ea4b73935b88f6c0a5a1345d
https://doi.org/10.1016/s0091-3057(01)00743-2
https://doi.org/10.1016/s0091-3057(01)00743-2
Autor:
Connie Sanchez, J Arnt
Publikováno v:
Behavioural Pharmacology. 11:291-298
The effects of serotonin (5-HT) receptor ligands on the MK 212 (6-chloro-2[1-piperazinyl]pyrazine) discriminative stimulus and quipazine-induced head twitches were studied in rats. 5-HT1A (8-OH-DPAT) and preferential 5-HT2A (DOI) receptor agonists di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bacd002b249b22e44bf5c4785e2e015
https://doi.org/10.1097/00008877-200006000-00012
https://doi.org/10.1097/00008877-200006000-00012
Publikováno v:
Behavioural Pharmacology. 5:119-124
Latent inhibition (LI) is a measure of retarded conditioning to a previously presented non-reinforced stimulus, that is impaired in schizophrenic patients and in rats treated with amphetamine. Neuroleptic drugs are known to produce two effects in thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da315ff4a50517b53c3503a9cc98cdb6
https://doi.org/10.1097/00008877-199404000-00002
https://doi.org/10.1097/00008877-199404000-00002
Publikováno v:
Journal of Medicinal Chemistry. 35:4823-4831
A series of 3-(4-fluorophenyl)-1H-indoles substituted in the 1-position with 4-piperidinyl, 1,2,3,6-tetrahydro-4-pyridinyl, and 4-piperazinyl was synthesized. By variation of the substituents in the benzene part of the indole nucleus in 1-[2-[4-[3-4-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7102058c8a614b9ad577693647a67a90
https://doi.org/10.1021/jm00104a007
https://doi.org/10.1021/jm00104a007
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 283(3)
The anxiolytic potential of the selective sigma2 ligand 1-[4-[1-(4-Fluorophenyl)-1H-indol-3-yl]-1-butyl]spiro[isobenzofuran-1(3H),4-piperidine] [corrected] (Lu 28-179) was assessed in various animal models of anxiety in rodents. Lu 28-179 facilitated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::039192f37894086d5a66b557497c261d
https://pubmed.ncbi.nlm.nih.gov/9400007
https://pubmed.ncbi.nlm.nih.gov/9400007
Akademický článek
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Akademický článek
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Autor:
J. Arnt
Publikováno v:
Behavioural pharmacology. 3(1)
The effects of sertindole, clozapine, Cis(Z)-flupentixol and haloperidol on the discriminative stimulus properties of d-amphetamine (dopamine DA stimulant), d-LSD (5-HT(2) agonist) and St 587 (alpha(1)-adrenoceptor agonist; 2-chloro-5-trifluoromethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5facb485bb9280641d019c54264c4785
https://pubmed.ncbi.nlm.nih.gov/11224097
https://pubmed.ncbi.nlm.nih.gov/11224097
Publikováno v:
Drugs of the Future. 33:0777
Schizophrenia is a debilitating syndrome consisting of several symptom dimensions (positive and negative symptoms; cognitive and mood disturbances) with a large unmet treatment need. Until now, the primary focus has been on the development of single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0b52112fe8c6cd584696128a3dd2c2d
https://doi.org/10.1358/dof.2008.033.09.1236966
https://doi.org/10.1358/dof.2008.033.09.1236966
Autor:
M. Didriksen, Mayke B. Hesselink, J.A. van der Heijden, J. Arnt, Feenstra Roelof W, C.G. Kruse
Publikováno v:
Schizophrenia Research. 60:104
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c4c42a68da8e48742ce67c720f55751
https://doi.org/10.1016/s0920-9964(03)80835-6
https://doi.org/10.1016/s0920-9964(03)80835-6