Zobrazeno 1 - 10
of 69
pro vyhledávání: '"J Andrea Mccart"'
Autor:
Laura Evgin, Carolina S Ilkow, Marie-Claude Bourgeois-Daigneault, Christiano Tanese de Souza, Lawton Stubbert, Michael S Huh, Victoria A Jennings, Monique Marguerie, Sergio A Acuna, Brian A Keller, Charles Lefebvre, Theresa Falls, Fabrice Le Boeuf, Rebecca A Auer, John D Lambris, J Andrea McCart, David F Stojdl, John C Bell
Publikováno v:
Molecular Therapy: Oncolytics, Vol 3, Iss C (2016)
The systemic delivery of therapeutic viruses, such as oncolytic viruses or vaccines, is limited by the generation of neutralizing antibodies. While pseudotyping of rhabdoviruses with the lymphocytic choriomeningitis virus glycoprotein has previously
Externí odkaz:
https://doaj.org/article/03318fbb20d24026bc983751bf71f24d
Autor:
Jessica G Tong, Yudith Ramos Valdes, John W Barrett, John C Bell, David Stojdl, Grant McFadden, J Andrea McCart, Gabriel E DiMattia, Trevor G Shepherd
Publikováno v:
Molecular Therapy: Oncolytics, Vol 2, Iss , Pp - (2015)
Epithelial ovarian cancer is unique among most carcinomas in that metastasis occurs by direct dissemination of malignant cells traversing throughout the intraperitoneal fluid. Accordingly, we test new therapeutic strategies using an in vitro three-di
Externí odkaz:
https://doaj.org/article/c244a8fac6094fe2bac70100a0881479
Autor:
Jari E Heikkilä, Markus J V Vähä-Koskela, Janne J Ruotsalainen, Miika W Martikainen, Marianne M Stanford, J Andrea McCart, John C Bell, Ari E Hinkkanen
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8603 (2010)
VA7 is a neurotropic alphavirus vector based on an attenuated strain of Semliki Forest virus. We have previously shown that VA7 exhibits oncolytic activity against human melanoma xenografts in immunodeficient mice. The purpose of this study was to de
Externí odkaz:
https://doaj.org/article/9e3d7804e4a04a5ba6d78d9f1539f147
Autor:
Heather MacTavish, Jean-Simon Diallo, Baocheng Huang, Marianne Stanford, Fabrice Le Boeuf, Naomi De Silva, Julie Cox, John Graydon Simmons, Tanya Guimond, Theresa Falls, J Andrea McCart, Harry Atkins, Caroline Breitbach, David Kirn, Stephen Thorne, John C Bell
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14462 (2010)
Histone deacetylase inhibitors (HDI) dampen cellular innate immune response by decreasing interferon production and have been shown to increase the growth of vesicular stomatitis virus and HSV. As attenuated tumour-selective oncolytic vaccinia viruse
Externí odkaz:
https://doaj.org/article/9e677ac797d4490e93fa86c33dbe4d1b
Autor:
Kathryn Ottolino-Perry, David Mealiea, Clara Sellers, Sergio A. Acuna, Fernando A. Angarita, Lili Okamoto, Deborah Scollard, Mihaela Ginj, Raymond Reilly, J. Andrea McCart
Publikováno v:
Molecular Therapy: Oncolytics, Vol 29, Iss , Pp 44-58 (2023)
Tumor-specific overexpression of receptors enables a variety of targeted cancer therapies, exemplified by peptide-receptor radiotherapy (PRRT) for somatostatin receptor (SSTR)-positive neuroendocrine tumors. While effective, PRRT is restricted to tum
Externí odkaz:
https://doaj.org/article/53c3449808d348409239ccf68f4a3076
Publikováno v:
Molecular Therapy: Oncolytics, Vol 22, Iss , Pp 85-97 (2021)
Vaccinia virus (VV) has emerged as a promising platform for oncolytic virotherapy. Many clinical VV candidates, such as the double-deleted VV, vvDD, are engineered with deletions that enhance viral tumor selectivity based on cellular proliferation ra
Externí odkaz:
https://doaj.org/article/c3b6fcb5d2cd445289edb54fe49a5ffd
Autor:
David H. Kirn, John C. Bell, J. Andrea McCart, Christina Addison, Fernando A. Angarita, Hannah Chen, Mong Cho, Jeong Heo, Tae-Ho Hwang, James Burke, Carolina Ilkow, Anne Moon, Manijeh Daneshmand, Richard Patt, Steve H. Thorne, Naomi De Silva, Rozanne Arulanandam, Caroline J. Breitbach
Supplementary Video 1 MPG file - 708K, 3-dimensional tumor model of 10 cm HCC tumor depicted in Fig. 4a (baseline; prior to JX-594 treatment). Beige = perfused; green = hypoperfused; red = necrotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bf5606107171f57f15cfe119441f3cf
https://doi.org/10.1158/0008-5472.22398998
https://doi.org/10.1158/0008-5472.22398998
Autor:
David H. Kirn, John C. Bell, J. Andrea McCart, Christina Addison, Fernando A. Angarita, Hannah Chen, Mong Cho, Jeong Heo, Tae-Ho Hwang, James Burke, Carolina Ilkow, Anne Moon, Manijeh Daneshmand, Richard Patt, Steve H. Thorne, Naomi De Silva, Rozanne Arulanandam, Caroline J. Breitbach
Supplementary Video 2 MPG file - 1158K, 3-dimensional tumor model of 10 cm HCC tumor depicted in Fig. 4b (baseline; 5 days post JX-594 treatment). Beige = perfused; green = hypoperfused; red = necrotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b340819ddcf122be950b5c642153296
https://doi.org/10.1158/0008-5472.22398995
https://doi.org/10.1158/0008-5472.22398995
Supplementary Figure 4 from Oncolytic Vaccinia Virus Disrupts Tumor-Associated Vasculature in Humans
Autor:
David H. Kirn, John C. Bell, J. Andrea McCart, Christina Addison, Fernando A. Angarita, Hannah Chen, Mong Cho, Jeong Heo, Tae-Ho Hwang, James Burke, Carolina Ilkow, Anne Moon, Manijeh Daneshmand, Richard Patt, Steve H. Thorne, Naomi De Silva, Rozanne Arulanandam, Caroline J. Breitbach
Supplementary Figure 4 PDF file - 69K, Day 5 enhancement waterfall plot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0773e0ef665ef3b1dbaf2cc5bca4a121
https://doi.org/10.1158/0008-5472.22399007
https://doi.org/10.1158/0008-5472.22399007
Supplementary Figure 3 from Oncolytic Vaccinia Virus Disrupts Tumor-Associated Vasculature in Humans
Autor:
David H. Kirn, John C. Bell, J. Andrea McCart, Christina Addison, Fernando A. Angarita, Hannah Chen, Mong Cho, Jeong Heo, Tae-Ho Hwang, James Burke, Carolina Ilkow, Anne Moon, Manijeh Daneshmand, Richard Patt, Steve H. Thorne, Naomi De Silva, Rozanne Arulanandam, Caroline J. Breitbach
Supplementary Figure 3 PDF file - 83K, Normal fibroblasts (GM38 cells) do not express VEGFR2 and are not sensitized to JX-594 infection upon incubation with VEGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6430c8697b2ea735847288099c883eaf
https://doi.org/10.1158/0008-5472.22399010.v1
https://doi.org/10.1158/0008-5472.22399010.v1