Zobrazeno 1 - 10
of 48
pro vyhledávání: '"J Alex Pasternak"'
Autor:
Amanda L Miller, J Alex Pasternak, Nicole J Medeiros, Lauren K Nicastro, Sarah A Tursi, Elizabeth G Hansen, Ryan Krochak, Akosiererem S Sokaribo, Keith D MacKenzie, Melissa B Palmer, Dakoda J Herman, Nikole L Watson, Yi Zhang, Heather L Wilson, R Paul Wilson, Aaron P White, Çagla Tükel
Publikováno v:
PLoS Pathogens, Vol 16, Iss 7, p e1008591 (2020)
Reactive arthritis, an autoimmune disorder, occurs following gastrointestinal infection with invasive enteric pathogens, such as Salmonella enterica. Curli, an extracellular, bacterial amyloid with cross beta-sheet structure can trigger inflammatory
Externí odkaz:
https://doaj.org/article/1badb525e2964d4b81ab1e7a66ba92da
Publikováno v:
BMC Veterinary Research, Vol 20, Iss 1, Pp 1-13 (2024)
Abstract Background Hypothyroidism is a common endocrine disruption observed in utero that adversely affects fetal growth and maturation leading to long-term impacts on health; however, the exact molecular mechanisms by which these deleterious effect
Externí odkaz:
https://doaj.org/article/29f84585258641c3b5f3779b76c679d1
Autor:
Haesu Ko, J. Alex Pasternak, Margaret K. Mulligan, Glenn Hamonic, Naresh Ramesh, Daniel J. MacPhee, Graham S. Plastow, John C. S. Harding
Publikováno v:
BMC Veterinary Research, Vol 20, Iss 1, Pp 1-16 (2024)
Abstract Background Porcine reproductive and respiratory syndrome virus 2 (PRRSV-2) infection during late gestation substantially lowers fetal viability and survival. In a previous genome-wide association study, a single nucleotide polymorphism on ch
Externí odkaz:
https://doaj.org/article/58c5c4b33127490a98036b3ecad2030e
Publikováno v:
Physiological Reports, Vol 12, Iss 8, Pp n/a-n/a (2024)
Abstract Thyroid hormones regulate metabolic rate, nutrient utilization, growth, and development. Swine are susceptible to thyroid suppression in response to disease or environmental conditions, but the physiological impact of such disruption has not
Externí odkaz:
https://doaj.org/article/6f01a56d49034df1a665acc09bf6ee89
Publikováno v:
Veterinary Research, Vol 53, Iss 1, Pp 1-14 (2022)
Abstract Porcine reproductive and respiratory syndrome virus (PRRSV) in late gestation causes a profound suppression of circulating maternal and fetal thyroid hormone during a critical window of development. To understand this relationship, we evalua
Externí odkaz:
https://doaj.org/article/0d1144fbd79b4957971c7f356aaca7cd
Publikováno v:
Veterinary Research, Vol 51, Iss 1, Pp 1-14 (2020)
Abstract To better understand the host response to porcine reproductive and respiratory virus-2 (PRRSV2) we evaluated circulating thyroid hormone and associated gene expression in a late gestation challenge model. Pregnant gilts were inoculated at ge
Externí odkaz:
https://doaj.org/article/3aecafb3eb2f4cee87019f9eec6c78be
Autor:
Glenn Hamonic, J. Alex Pasternak, Siew Hon Ng, Kezia R. Fourie, Olena M. Simko, Brodie Deluco, Heather L. Wilson
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
To protect the health of sows and gilts, significant investments are directed toward the development of vaccines against infectious agents that impact reproduction. We developed an intrauterine vaccine that can be delivered with semen during artifici
Externí odkaz:
https://doaj.org/article/9029b57b55cb4a31bd8b6da904021845
Autor:
Javier A. Barrera-Zarate, Susan E. Detmer, J. Alex Pasternak, Glenn Hamonic, Daniel J. MacPhee, John C. S. Harding
Publikováno v:
Veterinary Pathology. 59:940-949
Angiogenesis and cell proliferation in reproductive tissues are essential events for the maintenance of pregnancy, and alterations can lead to compromised fetal development and survival. Porcine reproductive and respiratory syndrome virus 2 (PRRSV-2)
Publikováno v:
Theriogenology. 184:162-170
Understanding why intrauterine growth restricted (IUGR) fetuses are more resilient to transplacental porcine reproductive and respiratory syndrome virus-2 (PRRSV-2) infection compared to normal fetuses may lead to alternative approaches to control PR
Autor:
Leah Thompson, J. Alex Pasternak, Ramjee Ghimire, D. Hashini Galhena Dissanayake, Nanda Joshi, Waleed Saleh, Paul Ebner
Publikováno v:
Journal of International Agricultural and Extension Education. 28:6-22