Zobrazeno 1 - 10
of 160
pro vyhledávání: '"J Alejandro Madrigal"'
Autor:
Richard C Duggleby, Hoi Pat Tsang, Kathryn Strange, Alasdair McWhinnie, Abigail A Lamikanra, David J Roberts, Diana Hernandez, J Alejandro Madrigal, Robert D Danby
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240190 (2020)
BackgroundAllogeneic haematopoietic cell transplantation (HCT) is a curative therapy for severe haematological disorders. However, it carries significant risk of morbidity and mortality. To improve patient outcomes, better graft selection strategies
Externí odkaz:
https://doaj.org/article/d08660afcf554d32af4b08c9efc2b30a
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186438 (2017)
Donation of haematopoietic stem cells, either through bone marrow (BM) or peripheral blood stem cell (PBSC) collection, is a generally safe procedure for healthy donors, although side effects are a known risk. Previous research, including our recent
Externí odkaz:
https://doaj.org/article/f8c541087167461f932d9a73abc30161
Autor:
Neema P Mayor, James Robinson, Alasdair J M McWhinnie, Swati Ranade, Kevin Eng, William Midwinter, Will P Bultitude, Chen-Shan Chin, Brett Bowman, Patrick Marks, Henny Braund, J Alejandro Madrigal, Katy Latham, Steven G E Marsh
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127153 (2015)
Allele-level resolution data at primary HLA typing is the ideal for most histocompatibility testing laboratories. Many high-throughput molecular HLA typing approaches are unable to determine the phase of observed DNA sequence polymorphisms, leading t
Externí odkaz:
https://doaj.org/article/6fdb794717194bb88757288f322ff6a8
Autor:
Aurore Saudemont, J Alejandro Madrigal
Publikováno v:
Haematologica, Vol 99, Iss 2 (2014)
Externí odkaz:
https://doaj.org/article/7ba92e406a22442581d8eaa8ae584be3
Publikováno v:
Archives of medical research. 53(8)
During the last five decades different therapies have been developed for the treatment of cancer, and as a result, patients can now live longer and better lives. Among such therapies, hematopoietic cell transplantation and immunotherapy have played k
Autor:
Effie W Petersdorf, Mary Carrington, Colm O'hUigin, Mats Bengtsson, Dianne De Santis, Valerie Dubois, Ted Gooley, Mary Horowitz, Katharine Hsu, J Alejandro Madrigal, Martin J Maiers, Mari Malkki, Caroline McKallor, Yasuo Morishima, Machteld Oudshoorn, Stephen R Spellman, Jean Villard, Phil Stevenson, Martin Maiers, Stephen Spellman, Jane Apperley, Peter Bardy, Ghislaine Bernard, Yves Bertrand, Adrian Bloor, Chiara Bonini, Stephane Buhler, Laura Bungener, Helen Campbell, Kristina Carlson, Ben Carpenter, Anne Cesbron, Christian Chabannon, Yves Chalandon, Jeremy Chapman, Réda Chebel, Patrice Chevallier, Gerda Choi, Matt Collin, Jan J Cornelissen, Charles Crawley, Lloyd D'Orsogna, Jean-Hugues Dalle, Eric Deconinck, Muriel DeMatteis, Mary Diviney, Anne Dormoy, Katia Gagne, Brenda Gibson, Maria Gilleece, David Gottlieb, John Gribben, Tayfun Güngör, Mike Haagenson, Cathie Hart, Rhonda Holdsworth, Ian Humphreys, Yoshihisa Kodera, Mickey Koh, Hélène Labussière-Wallet, Arjan C Lankester, Neubery Lardy, Sarah Lawson, Xavier Leleu, Stephen MacKinnon, Ram Malladi, Steven GE Marsh, Murray Martin, Neema P Mayor, I Grant McQuaker, Ellen Meijer, Satoko Morishima, Emmanouil Nikolousis, Kim Orchard, Jacob Passweg, Amit Patel, Katherine Patrick, Béatrice Pedron, Andy Peniket, Julia Perry, Eefke Petersen, Victoria Potter, Mike Potter, Rachel Protheroe, Nicole Raus, Carmen Ruiz de Elvira, Nigel Russell, Nicholaas PM Schaap, Urs Schanz, Harry Schouten, Roderick Skinner, John Snowden, Eric Spierings, Colin Steward, Eleni Tholouli, Alycia Thornton, Marcel Tilanus, Arnold van de Meer, Hendrik Veelkens, Paul Veys, Narelle Watson, Lyanne Weston, Keith Wilson, Marie Wilson, Robert Wynn, József Zsiros
Publikováno v:
The Lancet Haematology
The Lancet Haematology, Elsevier, 2021, 7 (1), pp.e50-e60. ⟨10.1016/s2352-3026(19)30208-x⟩
Petersdorf, E W, Carrington, M, O'hUigin, C, Bengtsson, M, De Santis, D, Dubois, V, Gooley, T, Horowitz, M, Hsu, K, Madrigal, J A, Maiers, M J, Malkki, M, McKallor, C, Morishima, Y, Oudshoorn, M, Spellman, S R, Villard, J, Stevenson, P & International Histocompatibility Working Group in Hematopoietic Cell Transplantation 2020, ' Role of HLA-B exon 1 in graft-versus-host disease after unrelated haemopoietic cell transplantation : a retrospective cohort study ', The Lancet Haematology, vol. 7, no. 1, pp. e50-e60 . https://doi.org/10.1016/S2352-3026(19)30208-X
The Lancet Haematology, 7(1), e50-e60. Lancet Publishing Group
The Lancet. Haematology, Vol. 7, No 1 (2020) pp. e50-e60
The Lancet Haematology, 7(1), E50-E60. ELSEVIER SCI LTD
The Lancet Haematology, 7(1), e50. Lancet Publishing Group
Lancet Haematol
The Lancet Haematology, Elsevier, 2021, 7 (1), pp.e50-e60. ⟨10.1016/s2352-3026(19)30208-x⟩
Petersdorf, E W, Carrington, M, O'hUigin, C, Bengtsson, M, De Santis, D, Dubois, V, Gooley, T, Horowitz, M, Hsu, K, Madrigal, J A, Maiers, M J, Malkki, M, McKallor, C, Morishima, Y, Oudshoorn, M, Spellman, S R, Villard, J, Stevenson, P & International Histocompatibility Working Group in Hematopoietic Cell Transplantation 2020, ' Role of HLA-B exon 1 in graft-versus-host disease after unrelated haemopoietic cell transplantation : a retrospective cohort study ', The Lancet Haematology, vol. 7, no. 1, pp. e50-e60 . https://doi.org/10.1016/S2352-3026(19)30208-X
The Lancet Haematology, 7(1), e50-e60. Lancet Publishing Group
The Lancet. Haematology, Vol. 7, No 1 (2020) pp. e50-e60
The Lancet Haematology, 7(1), E50-E60. ELSEVIER SCI LTD
The Lancet Haematology, 7(1), e50. Lancet Publishing Group
Lancet Haematol
Background: The success of unrelated haemopoietic cell transplantation (HCT) is limited by graft-versus-host disease (GVHD), which is the main post-transplantation challenge when HLA-matched donors are unavailable. A sequence dimorphism in exon 1 of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::195a18e65915d7d3471d1ddf38d8b61a
https://www.hal.inserm.fr/inserm-03349714/document
https://www.hal.inserm.fr/inserm-03349714/document
Autor:
Bronwen E. Shaw, Adrian Bloor, Chloe Anthias, Rachel Pearce, Daniel J. Weisdorf, Eleni Tholouli, Stephen Mackinnon, Marie C. Wilson, Julia Lee, Kim Orchard, Chrissy h. Roberts, WP Bultitude, Victoria T Potter, Sarah Cooley, Christian A. García-Sepúlveda, Jenny Byrne, Jeffrey S. Miller, Ram Malladi, Neema P. Mayor, Nigel H. Russell, J. Alejandro Madrigal, Steven G.E. Marsh, Richard Szydlo, Michael Potter, Amit Patel, I. Grant McQuaker, Jennifer Schellekens
Publikováno v:
Bone Marrow Transplant
The reported influence of donor Killer-cell Immunoglobulin-like Receptor (KIR) genes on the outcomes of haematopoietic cell transplantation (HCT) are contradictory, in part due to diversity of disease, donor sources, era and conditioning regimens wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b25c6cbbe121e3fcb012b89141a925
https://researchonline.lshtm.ac.uk/id/eprint/4656314/1/Original_submission_KIR_genotype_in_UK_HCT.pdf
https://researchonline.lshtm.ac.uk/id/eprint/4656314/1/Original_submission_KIR_genotype_in_UK_HCT.pdf
Autor:
J. Alejandro Madrigal, Richard C. Duggleby, Kathryn Strange, A.J. McWhinnie, Diana Hernandez, David J. Roberts, Robert Danby, Abigail A. Lamikanra, Hoi Pat Tsang
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240190 (2020)
PLoS ONE
PLoS ONE
BackgroundAllogeneic haematopoietic cell transplantation (HCT) is a curative therapy for severe haematological disorders. However, it carries significant risk of morbidity and mortality. To improve patient outcomes, better graft selection strategies
Autor:
Ted Gooley, Machteld Oudshoorn, Dianne De Santis, Valérie Dubois, Mari Malkki, Yasuo Morishima, Phil Stevenson, Katharina Fleischhauer, Stephen R. Spellman, Mats Bengtsson, Caroline McKallor, Jean Villard, Mary Carrington, Mary M. Horowitz, Effie W. Petersdorf, J. Alejandro Madrigal
Publikováno v:
Journal of Clinical Oncology, Vol. 38, No 24 (2020) pp. 2712-2718
J Clin Oncol
J Clin Oncol
PURPOSE The main aim of this study was to evaluate the significance of HLA-DPB1 expression in acute graft-versus-host disease (GVHD) after hematopoietic cell transplantation (HCT) from HLA-A, -B, -C, -DRB1, -DQB1–matched and –mismatched unrelated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e361445b2e8e4adbb765be09aa8d85
https://www.ncbi.nlm.nih.gov/pubmed/32479188
https://www.ncbi.nlm.nih.gov/pubmed/32479188
Autor:
J. Alejandro Madrigal, Michael P. Blundell, Mark W. Lowdell, Aurore Saudemont, Anna Domogala, Adrian J. Thrasher
Publikováno v:
Cytotherapy. 19:710-720
Background aims Natural killer (NK) cells have the potential to become a successful immunotherapy as they can target malignant cells without being direct effectors of graft-versus-host disease. Our group has previously shown that large numbers of fun