Zobrazeno 1 - 10
of 22
pro vyhledávání: '"J A Zwiebel"'
Publikováno v:
The Journal of Immunology. 152:3294-3305
Recent studies of transgenic mice have confirmed that clonal deletion is involved in the development of B cells. However, little is known about intercellular and intracellular molecular events regulating B cell clonal deletion. We investigated the ro
Autor:
J A Zwiebel
Publikováno v:
Leukemia. 14:488-490
New agents for the treatment of acute myelogenous leukemia are discussed that reflect different treatment mechanisms. These include histone acetylation, angiogenesis inhibition, protein kinase inhibitors, and a novel retinoid. Efficacy and safety in
Publikováno v:
Journal of Virology. 65:6365-6370
Nonimmortalized mouse mammary epithelial cells expressing Escherichia coli beta-galactosidase from a murine amphotropic packaged retroviral vector were injected into the epithelium-divested mammary fat pads of syngeneic mice. Mammary glands formed fr
Publikováno v:
Seminars in oncology. 27(5)
Few chemotherapy agents have demonstrated activity in patients with myelodysplastic syndromes (MDS) and supportive management remains the standard of care. An increasing number of new drugs in development are being directed at specific molecular or b
Autor:
J A, Zwiebel, B D, Cheson
Publikováno v:
Seminars in oncology. 25(1)
While both the Rai and Binet staging systems continue to provide the most useful tools for assessing prognosis in chronic lymphocytic leukemia (CLL), both fail to identify subsets of patients that may, or may not, benefit from therapy. While numerous
Publikováno v:
Clinicalexperimental metastasis. 15(2)
Bone is a common metastatic site in human breast cancer (HBC). Since bone metastasis occurs very rarely from current spontaneous or experimental metastasis models of HBC cells in nude mice, an arterial seeding model involving the direct injection of
Publikováno v:
Zhonghua bing li xue za zhi = Chinese journal of pathology. 25(4)
Since interleukin 2 (IL-2) can stimulat host immune response, the cDNA encoding human IL-2 (hIL-2), mediated by retroviral vector, was transferred into human breast carcinoma cell line "MDA-MB-435". The characterization and tumorigenesis of hIL-2 gen
Publikováno v:
Cytokines and molecular therapy. 2(2)
Recent studies have demonstrated the feasibility of cytokine gene transfer to enhance the antitumor activities of host immune cells. Endothelial cells forming the vascular supply of tumors may be useful vehicles for the delivery of cytokine molecules
Publikováno v:
Cancer research. 55(11)
By virtue of their location within blood vessels and their ability to express foreign genes, endothelial cells are attractive vehicles for the delivery of therapeutic molecules in vivo. We wished to determine whether i.v.-injected, genetically modifi
Autor:
J. A. Zwiebel
Publikováno v:
Hereditary Diseases and Blood Transfusion ISBN: 9781461358343
Initially viewed principally as a means of treating inherited genetic diseases, gene therapy is now seen as a promising approach for virtually all kinds of disorders, and by disciplines as diverse as oncology, cardiology, endocrinology, and infectiou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::938213add8082e1c2b266b9e5c334454
https://doi.org/10.1007/978-1-4615-2017-7_16
https://doi.org/10.1007/978-1-4615-2017-7_16