Zobrazeno 1 - 10
of 3 508
pro vyhledávání: '"J A Wood"'
Autor:
Gareth Hazell, Eve McCallion, Nina Ahlskog, Emma R. Sutton, Magnus Okoh, Emad I. H. Shaqoura, Joseph M. Hoolachan, Taylor Scaife, Sara Iqbal, Amarjit Bhomra, Anna J. Kordala, Frederique Scamps, Cedric Raoul, Matthew J. A. Wood, Melissa Bowerman
Publikováno v:
Skeletal Muscle, Vol 14, Iss 1, Pp 1-24 (2024)
Abstract Background Amyotrophic lateral sclerosis (ALS) is a devastating and incurable neurodegenerative disease. Accumulating evidence strongly suggests that intrinsic muscle defects exist and contribute to disease progression, including imbalances
Externí odkaz:
https://doaj.org/article/b34e721524b14bc599fbd8a446eb5ca2
Autor:
C. A. Lindstrøm, J. Beinortaitė, J. Björklund Svensson, L. Boulton, J. Chappell, S. Diederichs, B. Foster, J. M. Garland, P. González Caminal, G. Loisch, F. Peña, S. Schröder, M. Thévenet, S. Wesch, M. Wing, J. C. Wood, R. D’Arcy, J. Osterhoff
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Radio-frequency particle accelerators are engines of discovery, powering high-energy physics and photon science, but are also large and expensive due to their limited accelerating fields. Plasma-wakefield accelerators (PWFAs) provide orders-
Externí odkaz:
https://doaj.org/article/91b99bf2bff04e8b8199309c9ee28846
Publikováno v:
Frontiers in Animal Science, Vol 5 (2024)
Consumption of animal-derived foods (ADFs), particularly red meat, is declining in high-income countries because of concerns over health and the effects on climate change but is increasing in low- and middle-income countries. As a group of foods, ADF
Externí odkaz:
https://doaj.org/article/3a4104e6ce204cc09ed5033e1cd91077
Autor:
Scott E. Bonner, Simonides I. van deWakker, William Phillips, Eduard Willms, Joost P. G. Sluijter, Andrew F. Hill, Matthew J. A. Wood, Pieter Vader
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 2, Pp n/a-n/a (2024)
Abstract Extracellular vesicles (EVs) are cell derived membranous nanoparticles. EVs are important mediators of cell–cell communication via the transfer of bioactive content and as such they are being investigated for disease diagnostics as biomark
Externí odkaz:
https://doaj.org/article/add20762f9074cf6b277f96e8773807b
Publikováno v:
British Journal of Pharmacy, Vol 8, Iss 2 (2023)
The major biopharmaceutics challenge faced during the development of subcutaneous (SC) drug products is the limited understanding of the physiological factors and the combination product attributes that can impact absorption rate/extent and drug prod
Externí odkaz:
https://doaj.org/article/43939625bcab44cf8c2161de116ddca4
Autor:
Ysobel R. Baker, Cameron Thorpe, Jinfeng Chen, Laura M. Poller, Lina Cox, Pawan Kumar, Wooi F. Lim, Lillian Lie, Graham McClorey, Sven Epple, Daniel Singleton, Michael A. McDonough, Jack S. Hardwick, Kirsten E. Christensen, Matthew J. A. Wood, James P. Hall, Afaf H. El-Sagheer, Tom Brown
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Oligonucleotides targeting mRNA are promising therapeutic agents but suffer from poor bioavailability. Here, the authors develop reduced-charge oligonucleotides with artificial LNA-amide linkages with improved cell uptake and minimal structural devia
Externí odkaz:
https://doaj.org/article/9f5986b8806645e7a8826174637171fa
Publikováno v:
Geoscientific Model Development, Vol 14, Pp 6741-6763 (2021)
At the leaf level, stomata control the exchange of water and carbon across the air–leaf interface. Stomatal conductance is typically modeled empirically, based on environmental conditions at the leaf surface. Recently developed stomatal optimizatio
Externí odkaz:
https://doaj.org/article/282eb89c92e440d79b1df536d44a4e85
Autor:
Ghulam Hassan Dar, Cláudia C. Mendes, Wei-Li Kuan, Alfina A. Speciale, Mariana Conceição, André Görgens, Inna Uliyakina, Miguel J. Lobo, Wooi F. Lim, Samir EL Andaloussi, Imre Mäger, Thomas C. Roberts, Roger A. Barker, Deborah C. I. Goberdhan, Clive Wilson, Matthew J. A. Wood
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
GAPDH is generally considered a housekeeping gene and functions in glycolysis. Here, the authors show that GAPDH has a role in promoting vesicle clustering in endosomes and can load siRNA onto the surface of extracellular vesicles, which can be explo
Externí odkaz:
https://doaj.org/article/b286aa9a491c4fbfb8a3ac8161e8f868
Publikováno v:
Frontiers in Ecology and Evolution, Vol 10 (2022)
Ecological processes are complex, often exhibiting non-linear, interactive, or hierarchical relationships. Furthermore, models identifying drivers of phenology are constrained by uncertainty regarding predictors, interactions across scales, and legac
Externí odkaz:
https://doaj.org/article/1130aaab0be74ab1a29e4afa4dfbea91
Publikováno v:
ACS Omega, Vol 6, Iss 5, Pp 3483-3489 (2021)
Externí odkaz:
https://doaj.org/article/5ae6869c1bf94457bda4790b01c8bf84