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pro vyhledávání: '"J A Treitman"'
Autor:
E S Neiss, Samm T. Portelli, R A Vukovich, P E Grebow, N C Tantillo, E P Barry, J A Treitman, D J Blasucci
Publikováno v:
European Journal of Clinical Pharmacology. 22:295-299
Two formulations of indapamide tablets (2.5 mg) were given as a 5.0 mg dose and the subsequent blood levels were compared to those obtained after administration of a 5.0 mg solution. The study was conducted as a randomized three-way crossover design
Publikováno v:
Research communications in chemical pathology and pharmacology. 42(2)
Renal impairment can affect the disposition of metabolites, as well as unchanged drug, especially when there is significant renal clearance of metabolites. The pharmacokinetics of indapamide, a highly metabolized drug, and total indapamide equivalent