Zobrazeno 1 - 10
of 925
pro vyhledávání: '"J A Trapani"'
Autor:
L. H. Porter, J. J. Zhu, N. L. Lister, S. G. Harrison, S. Keerthikumar, D. L. Goode, R. Quezada Urban, D. J. Byrne, A. Azad, I. Vela, M. S. Hofman, P. J. Neeson, P. K. Darcy, J. A. Trapani, R. A. Taylor, G. P. Risbridger
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Chimeric antigen receptor (CAR) T cells have transformed the treatment landscape for hematological malignancies. However, CAR T cells are less efficient against solid tumors, largely due to poor infiltration resulting from the immunosuppress
Externí odkaz:
https://doaj.org/article/eb8dadc0a7e045c7b9cf4a1d7631aa08
Autor:
M. Welz, S. Eickhoff, Z. Abdullah, J. Trebicka, K. H. Gartlan, J. A. Spicer, A. J. Demetris, H. Akhlaghi, M. Anton, K. Manske, D. Zehn, B. Nieswandt, C. Kurts, J. A. Trapani, P. Knolle, D. Wohlleber, W. Kastenmüller
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
CD8 T cells can protect the liver from viral infection, but can also result in severe liver damage and organ failure. Here, the authors develop a mouse model reflecting fulminant CD8 T cell mediated viral hepatitis, which occurs in a perforin-depende
Externí odkaz:
https://doaj.org/article/a16f075282c8487babc56ea336c15431
Publikováno v:
Methods in cell biology. 133
During sensory transduction, external physical stimuli are translated into an internal biological signal. In vertebrates, hair cells are specialized mechanosensory receptors that transduce sound, gravitational forces, and head movements into electric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::16ce18bd7d03200c8ce6ce0c784b83c8
https://pubmed.ncbi.nlm.nih.gov/27263416
https://pubmed.ncbi.nlm.nih.gov/27263416
Autor:
Zhu, Ying‐Qin1 (AUTHOR), Huang, Yue2 (AUTHOR), Shi, Yin‐Hao1 (AUTHOR), Huang, Chen‐Song1 (AUTHOR), Zhao, Guang‐Yin3 (AUTHOR), Liu, Zhi‐De1 (AUTHOR), Ma, Ming‐Jian1 (AUTHOR), Ye, Jing‐Yuan1 (AUTHOR), Xu, Xiang1 (AUTHOR), Liu, Qi1 (AUTHOR), Huang, Xi‐Tai1 (AUTHOR), Wang, Jie‐Qin4 (AUTHOR), Xu, Qiong‐Cong1 (AUTHOR) xuqc5@mail.sysu.edu.cn, Yin, Xiao‐Yu1 (AUTHOR) yinxy@mail.sysu.edu.cn
Publikováno v:
Advanced Science. 12/18/2024, Vol. 11 Issue 47, p1-15. 15p.
Autor:
Ding, Ling1,2 (AUTHOR), Guo, Hongjie1,3 (AUTHOR), Zhang, Jie1 (AUTHOR), Zheng, Mingming1 (AUTHOR), Zhang, Wenjie1 (AUTHOR), Wang, Longsheng1 (AUTHOR), Du, Qianqian1 (AUTHOR), Zhou, Chen1 (AUTHOR), Xu, Yanjun4 (AUTHOR), Wu, Honghai1 (AUTHOR), He, Qiaojun1,5,6 (AUTHOR) qiaojunhe@zju.edu.cn, Yang, Bo1,3,5 (AUTHOR) yang924@zju.edu.cn
Publikováno v:
Advanced Science. 11/6/2024, Vol. 11 Issue 41, p1-16. 16p.
Publikováno v:
The Journal of Immunology. 158:5783-5790
Two pathways have been implicated in the induction of apoptosis by cytotoxic T cells: the granule exocytosis pathway and a pathway using CD95 (Fas/APO-1). To test whether apoptosis induced by either of these pathways could be blocked by Bcl-2, we exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dd13c4bf05b3126d29f323db5b72fc8
https://doi.org/10.4049/jimmunol.158.12.5783
https://doi.org/10.4049/jimmunol.158.12.5783
Publikováno v:
Tissue antigens. 80(6)
Granzymes (Grz) are a family of serine proteases found in the granules of cytotoxic lymphocytes and are emerging as an important group of proteins involved in immune function and surveillance. Grz have both cytotoxic and more recently reported non-cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7c2bf103d01f596849f1fdeabef45c13
https://pubmed.ncbi.nlm.nih.gov/23137319
https://pubmed.ncbi.nlm.nih.gov/23137319
Autor:
Liu, Tao1 (AUTHOR), Xu, LiFang2 (AUTHOR), Shen, Yuqing2 (AUTHOR), Chen, Zefang3 (AUTHOR), Yao, Juan4 (AUTHOR), Mo, Lin2 (AUTHOR) molin999@126.com
Publikováno v:
Cancer Medicine. Oct2024, Vol. 13 Issue 19, p1-10. 10p.
Autor:
Li, Youyou1 (AUTHOR), Liu, Jing1,2 (AUTHOR), Weichselbaum, Ralph R.2 (AUTHOR), Lin, Wenbin1,2 (AUTHOR) wenbinlin@uchicago.edu
Publikováno v:
Advanced Science. 9/18/2024, Vol. 11 Issue 35, p1-11. 11p.
Autor:
Liu, Yen‐Cheng1 (AUTHOR), Ansaryan, Saeid1 (AUTHOR), Tan, Jiayi1 (AUTHOR), Broguiere, Nicolas2 (AUTHOR), Lorenzo‐Martín, Luis Francisco2 (AUTHOR), Homicsko, Krisztian3,4,5,6 (AUTHOR), Coukos, George3,4,5,6 (AUTHOR), Lütolf, Matthias P.2 (AUTHOR), Altug, Hatice1 (AUTHOR) hatice.altug@epfl.ch
Publikováno v:
Advanced Science. 9/11/2024, Vol. 11 Issue 34, p1-15. 15p.