Zobrazeno 1 - 10
of 23
pro vyhledávání: '"J A Pachter"'
Publikováno v:
Biochemical Journal. 294:153-158
To evaluate the role of protein kinase C (PKC) in regulation of cellular responsiveness to mitogens, we used rat 6 (R6) fibroblasts that stably overexpress the beta 1 isoenzyme of protein kinase C (PKC-beta 1). The potent vasoconstrictor and mitogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa05f8084f124be5784b7009378a7185
https://doi.org/10.1042/bj2940153
https://doi.org/10.1042/bj2940153
Publikováno v:
Proceedings of the National Academy of Sciences. 88:598-602
We are using a Rat-6 fibroblast cell line that stably overexpresses the beta 1 isozyme of protein kinase C (PKC) to study regulation of phospholipid hydrolysis by PKC. Stimulation of control (R6-C1) or overexpressing (R6-PKC3) cells with phorbol este
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c045235baf9909b2836e4c417a366cd8
https://doi.org/10.1073/pnas.88.2.598
https://doi.org/10.1073/pnas.88.2.598
Publikováno v:
Journal of Biological Chemistry. 265:8989-8992
We have previously determined that beta-adrenergic and somatostatin receptors stimulate and inhibit, respectively, Na-H exchange independent of changes in cAMP accumulation (Barber, D.L., McGuire, M.E., and Ganz, M.B. (1989) J. Biol. Chem. 264, 21038
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b63466df7398b3e53eca44186d84b11
https://doi.org/10.1016/s0021-9258(19)38800-3
https://doi.org/10.1016/s0021-9258(19)38800-3
Publikováno v:
Biochemical Journal. 267:359-364
Thapsigargin stimulates an increase of cytosolic free Ca2+ concentration [( Ca2+]c) in, and 45Ca2+ efflux from, a clone of GH4C1 pituitary cells. This increase in [Ca2+]c was followed by a lower sustained elevation of [Ca2+]c, which required the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::591bf61605ea2e5c681900b6d8c32e99
https://doi.org/10.1042/bj2670359
https://doi.org/10.1042/bj2670359
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 37(2)
A novel method for qualitative and quantitative analysis of monocyte transendothelial migration is described. By labeling monocytes and endothelial cells with different fluorophores, and utilizing confocal microscopy and three-dimensional image recon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b6928d904f46d3aa6845b4cfb5b52dd2
https://pubmed.ncbi.nlm.nih.gov/11332736
https://pubmed.ncbi.nlm.nih.gov/11332736
Publikováno v:
Journal of leukocyte biology. 68(4)
As astrocytes are a source of monocyte chemoattractant protein-1 (MCP-1) and lie in close apposition to brain microvessels, interactions between astrocytes and infiltrating monocytes might regulate production of this chemokine. To investigate this po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e7a4b520fcc2f5f5c9c1abc467843b96
https://pubmed.ncbi.nlm.nih.gov/11037977
https://pubmed.ncbi.nlm.nih.gov/11037977
Autor:
R B, Weltzien, J S, Pachter
Publikováno v:
Journal of neuroscience research. 59(4)
Previous studies from this laboratory have shown that human monocytes exposed to beta-amyloid peptide (Abeta) exert a graded neurotoxic response in an organotypic brain culture paradigm. Moreover, this toxicity can be reduced by compounds that inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5eb462ec6f7fa4d82d8e723ab0d7947
https://pubmed.ncbi.nlm.nih.gov/10679791
https://pubmed.ncbi.nlm.nih.gov/10679791
Autor:
A V, Andjelkovic, J S, Pachter
Publikováno v:
Journal of neuroscience research. 51(4)
Accumulating evidence points toward a significant role for the microvascular endothelium in the pathogenesis of several neurologic conditions. This review highlights those biochemical, anatomical, and physiological features of the endothelium thought
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::57fa6ea3629a33efc24b5e199935a8e9
https://pubmed.ncbi.nlm.nih.gov/9514196
https://pubmed.ncbi.nlm.nih.gov/9514196
Autor:
Erik H.J. Danen, Dirk J. Ruiter, A.A. van Kraats, I. M. H. A. Cornelissen, J. A. Pachter, Cezary Marcinkiewicz, Stefan Niewiarowski, G.N.P. van Muijen
Publikováno v:
Experimental Cell Research, 238, pp. 188-196
Experimental Cell Research, 238, 188-196
Experimental Cell Research, 238, 188-196
Peptides containing the integrin recognition sequence, RGD, can inhibit experimental metastasis of mouse melanoma cells, but the integrin(s) affected in these experiments is unknown. Besides "classical" RGD-binding integrins such as alpha 5 beta 1 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa27d9400625083172c9e61c7b21e84
https://pubmed.ncbi.nlm.nih.gov/9457071
https://pubmed.ncbi.nlm.nih.gov/9457071
Autor:
J A, Pachter
Publikováno v:
Nursing spectrum (D.C./Baltimore metro ed.). 7(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d017f5a4d14cf116da61d5d77e6f7c51
https://pubmed.ncbi.nlm.nih.gov/9431213
https://pubmed.ncbi.nlm.nih.gov/9431213