Zobrazeno 1 - 10
of 52
pro vyhledávání: '"J A McKinna"'
Autor:
Mitchell Dowsett, Judith Gledhill, J. Alan McKinna, Alan Ashworth, Ian E. Smith, Joanne E. Nicholls, Carolyn M. Ryde, Valentine M. Macaulay
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 44:605-609
Three approaches have been taken to elucidate further the biological importance of intratumoural aromatase activity. (i) MCF7 and T47D hormone-dependent breast cancer cell lines both showed detectable aromatase activity in vitro. The up-regulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::413f5628844e1b7290e95ab58651c321
https://doi.org/10.1016/0960-0760(93)90266-y
https://doi.org/10.1016/0960-0760(93)90266-y
Autor:
I.E. Smith, J. A. McKinna, Michael Jarman, S.R.D. Johnston, Michael Baum, Griggs Lj, Ben P. Haynes, Mitchell Dowsett, N. Sacks
Publikováno v:
Breast Cancer Research and Treatment. 28:241-250
While the presence of oestrogen receptors (ERs) in human breast cancer may determine the biological response to tamoxifen, the extent to which ER status governs tumour tamoxifen accumulation is unclear. We investigated the intra-tumoural disposition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63471ce49e41f884a0bc1ce6e9660336
https://doi.org/10.1007/bf00666585
https://doi.org/10.1007/bf00666585
Autor:
J. A. McKINNA, M. Dowsett, H. Minasian, N. King, C. M. Ryde, D. Smith, K. Maclennan, P.A. Trott
Publikováno v:
Cytopathology. 3:155-160
Four methods of assessing oestrogen receptor (ER) status were compared in 33 patients with operable primary breast cancer. the methods used to assess the ER status were immunocyto-chemical assay (ER-ICA) of frozen sections, fine needle aspirates and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d531b889660da4290294e2aa448ca66c
https://doi.org/10.1111/j.1365-2303.1992.tb00041.x
https://doi.org/10.1111/j.1365-2303.1992.tb00041.x
Publikováno v:
Cancer. 69:2271-2275
Metastases from cystosarcoma phyllodes are rare, and treatment generally is ineffective. Four patients were treated with ifosfamide (alone in three and combined with doxorubicin in one). Two patients had complete remissions that lasted 26 and 61+ mon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94c0f423d3d8744f61c38dceb8611464
https://doi.org/10.1002/1097-0142(19920501)69:9<2271::aid-cncr2820690911>3.0.co
https://doi.org/10.1002/1097-0142(19920501)69:9<2271::aid-cncr2820690911>3.0.co
Publikováno v:
Annals of the Royal College of Surgeons of England. 66(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4b27c1974950933c7a5a2bf8424799e
https://pubmed.ncbi.nlm.nih.gov/19310925
https://pubmed.ncbi.nlm.nih.gov/19310925
Autor:
J. A. McKinna, Janine Mansi, Stanley W. Ashley, G. Walsh, Duncan I. Jodrell, I.E. Smith, H. D. Sinnett, M. C. Pearson
Publikováno v:
British Journal of Cancer
Mitozantrone (Novantrone) has recently been incorporated into a new combination chemotherapy regimen with mitomycin-C and methotrexate (MMM) against advanced breast cancer. We have compared MMM (mitozantrone 8 mg m-2 i.v. q 3 weekly, methotrexate 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b5674974e23ae55b726ca5933ef3d03
https://doi.org/10.1038/bjc.1991.176
https://doi.org/10.1038/bjc.1991.176
Autor:
A. L. Jones, Jane B. Davey, Sue Ashley, Jennifer Treleaven, J. Alan McKinna, Trevor J. Powles, Colin R. Tillyer
Publikováno v:
European Journal of Cancer and Clinical Oncology. 26:680-684
An ‘anti-oestrogen’ such as tamoxifen may project prophylactically against breast cancer. At the Royal Marsden Hospital, the blind randomised feasibility study of tamoxifen 20 mg per day versus placebo in 200 healthy women has been extended into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d36c099724aa94348be1af4f77f95d41
https://doi.org/10.1016/0277-5379(90)90116-b
https://doi.org/10.1016/0277-5379(90)90116-b
Publikováno v:
Journal of clinical pathology. 47(3)
AIMS--(i) To assess the validity of an immunocytochemical technique for detecting pS2 protein in paraffin wax embedded tissue; (ii) to provide further data on the relation between pS2 protein and oestrogen receptor (ER) and progesterone receptor (PgR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e7c89cc83e44e47ebd3323ebdf064f4
https://pubmed.ncbi.nlm.nih.gov/8163696
https://pubmed.ncbi.nlm.nih.gov/8163696
Publikováno v:
Cancer. 69(9)
Metastases from cystosarcoma phyllodes are rare, and treatment generally is ineffective. Four patients were treated with ifosfamide (alone in three and combined with doxorubicin in one). Two patients had complete remissions that lasted 26 and 61+ mon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a55276602495474eedfd402285a80b89
https://pubmed.ncbi.nlm.nih.gov/1314127
https://pubmed.ncbi.nlm.nih.gov/1314127
Autor:
J. Alan McKinna, Jane B. Davey, Geraldine A. Walsh, Roger P. A'Hern, Gay Curling, Heidi Frankland, Jennifer Viggers
Publikováno v:
European journal of cancer (Oxford, England : 1990). (4-5)
Over 30 000 women with minimal symptoms were examined between 1968 and 1987 for the detection of early stage breast cancer. Subsequent follow-up screening was selected for women at higher risk because of family history, previous significant benign br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ddaddb3a3d2d69f9b4205da68bc4199
https://pubmed.ncbi.nlm.nih.gov/1524923
https://pubmed.ncbi.nlm.nih.gov/1524923