Zobrazeno 1 - 10
of 866
pro vyhledávání: '"J A Lawson"'
Autor:
Edem Magdalene Afua Tette, Ebenezer V. Badoe, Nyonuku A. Baddoo, Henry J. O. Lawson, Samuel Pie, Edmund T. Nartey, Margaret Y. Lartey
Publikováno v:
International Medical Education, Vol 3, Iss 3, Pp 239-256 (2024)
Child abuse affects millions of children globally. Comprehensive training is essential to promote its recognition and trigger appropriate responses to prevent missed opportunities for intervention. We describe a child abuse and child protection train
Externí odkaz:
https://doaj.org/article/fe820bbf81464bc0b1aa235610375db6
Autor:
L. M. Chu, D. C. Rennie, S Kirychuk, D Cockcroft, J. R. Gordon, W Pickett, J Dosman, J. A. Lawson
Publikováno v:
Journal of Agromedicine. :1-13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaadb8e7e87b404a4ed315bc9cee67db
https://doi.org/10.1080/1059924x.2023.2200427
https://doi.org/10.1080/1059924x.2023.2200427
Autor:
Henry J. O. Lawson, David N. N. Nortey
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Introduction: Family Medicine is a growing specialty in the medical world. While it is expected that the specialty should have its own unique and established core values and tasks, the breath of the practice in several countries of the world has made
Externí odkaz:
https://doaj.org/article/93d80188f6de42989a7d58df9276e041
Publikováno v:
BMC Veterinary Research, Vol 14, Iss 1, Pp 1-11 (2018)
Abstract Background Chronic kidney disease (CKD) is common in geriatric cats, and the most prevalent pathology is chronic tubulointerstitial inflammation and fibrosis. The cell type predominantly responsible for the production of extra-cellular matri
Externí odkaz:
https://doaj.org/article/ad6ae265288b47ffbdeccf6bf45888b9
Autor:
Jill Hallin, Vickie Bowcut, Andrew Calinisan, David M. Briere, Lauren Hargis, Lars D. Engstrom, Jade Laguer, James Medwid, Darin Vanderpool, Ella Lifset, David Trinh, Natalie Hoffman, Xiaolun Wang, J. David Lawson, Robin J. Gunn, Christopher R. Smith, Nicole C. Thomas, Matthew Martinson, Alex Bergstrom, Francis Sullivan, Karyn Bouhana, Shannon Winski, Leo He, Julio Fernandez-Banet, Adam Pavlicek, Jacob R. Haling, Lisa Rahbaek, Matthew A. Marx, Peter Olson, James G. Christensen
Publikováno v:
Nature Medicine. 28:2171-2182
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d677a7e099fb8459d3aaad7bbf29b468
https://doi.org/10.1038/s41591-022-02007-7
https://doi.org/10.1038/s41591-022-02007-7
Autor:
John M. Ketcham, Jacob Haling, Shilpi Khare, Vickie Bowcut, David M. Briere, Aaron C. Burns, Robin J. Gunn, Anthony Ivetac, Jon Kuehler, Svitlana Kulyk, Jade Laguer, J. David Lawson, Krystal Moya, Natalie Nguyen, Lisa Rahbaek, Barbara Saechao, Christopher R. Smith, Niranjan Sudhakar, Nicole C. Thomas, Laura Vegar, Darin Vanderpool, Xiaolun Wang, Larry Yan, Peter Olson, James G. Christensen, Matthew A. Marx
Publikováno v:
Journal of Medicinal Chemistry. 65:9678-9690
SOS1 is one of the major guanine nucleotide exchange factors that regulates the ability of KRAS to cycle through its "on" and "off" states. Disrupting the SOS1:KRAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe52dccfc91d77da8d18ff2be215969
https://doi.org/10.1021/acs.jmedchem.2c00741
https://doi.org/10.1021/acs.jmedchem.2c00741
Autor:
Patrick Vincent, Barbara Hibner, Ron de Jong, Hidehisa Iwata, Akio Mizutani, Akira Hori, Kengo Okada, J. David Lawson, Shaosong Chu, Ruhi Kamran, Mark S. Hixon, Shweta Pandya, Deepika Balakrishna, Jennifer Matuszkiewicz, Pamela J. Farrell
Supplemental Table 1. Activity of MET TKIs in enzyme and cellular assessments Supplemental Table 2. Activity of Compound 1 against approximately 130 additional protein kinases. Figure S1. Binding modes of selective MET TKIs. Figure S2. MET TKI, Compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120f016d9ddd8b8907dbb9ab603d8673
https://doi.org/10.1158/1535-7163.22504134
https://doi.org/10.1158/1535-7163.22504134
Autor:
Patrick Vincent, Barbara Hibner, Ron de Jong, Hidehisa Iwata, Akio Mizutani, Akira Hori, Kengo Okada, J. David Lawson, Shaosong Chu, Ruhi Kamran, Mark S. Hixon, Shweta Pandya, Deepika Balakrishna, Jennifer Matuszkiewicz, Pamela J. Farrell
Receptor tyrosine kinase therapies have proven to be efficacious in specific cancer patient populations; however, a significant limitation of tyrosine kinase inhibitor (TKI) treatment is the emergence of resistance mechanisms leading to a transient,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a781388f16b2563b61d0736ccfdad587
https://doi.org/10.1158/1535-7163.c.6537630
https://doi.org/10.1158/1535-7163.c.6537630
Autor:
Tom E. Forshaw, Julie A. Reisz, Kimberly J. Nelson, Rajesh Gumpena, J. Reed Lawson, Thomas J. Jönsson, Hanzhi Wu, Jill E. Clodfelter, Lynnette C. Johnson, Cristina M. Furdui, W. Todd Lowther
Publikováno v:
Antioxidants, Vol 10, Iss 6, p 946 (2021)
Human peroxiredoxins (Prx) are a family of antioxidant enzymes involved in a myriad of cellular functions and diseases. During the reaction with peroxides (e.g., H2O2), the typical 2-Cys Prxs change oligomeric structure between higher order (do)decam
Externí odkaz:
https://doaj.org/article/d55fdb246166416a82421dcc5de5c96d
Autor:
Christopher R. Smith, Ruth Aranda, Thomas P. Bobinski, David M. Briere, Aaron C. Burns, James G. Christensen, Jeffery Clarine, Lars D. Engstrom, Robin J. Gunn, Anthony Ivetac, Ronald Jean-Baptiste, John M. Ketcham, Masakazu Kobayashi, Jon Kuehler, Svitlana Kulyk, J. David Lawson, Krystal Moya, Peter Olson, Lisa Rahbaek, Nicole C. Thomas, Xiaolun Wang, Laura M. Waters, Matthew A. Marx
Publikováno v:
Journal of Medicinal Chemistry. 65:1749-1766
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6807ba018e034c41898a959b92d453dc
https://doi.org/10.1021/acs.jmedchem.1c01900
https://doi.org/10.1021/acs.jmedchem.1c01900