Zobrazeno 1 - 10
of 16
pro vyhledávání: '"J A Fabry"'
Autor:
Dominique Beydon, J. P. Payan, F. Gallissot, Jean-Philippe Sabaté, J. P. Fabry, I. Langonne, Anne-Marie Saillenfait
Publikováno v:
Food and Chemical Toxicology. 37:1089-1096
Sprague-Dawley rats were administered 1,2-diethylbenzene (1,2-DEB) by gavage on gestational days (GD) 6 through 20 at dose levels of 0 (corn oil), 5, 15, 25 or 35 mg/kg. The dams were euthanized on GD21 and the offspring were weighed and examined for
Autor:
A. M. Saillenfait, J. P. Payan, J. P. Fabry, D. Beydon, I. Langonne, F. Gallissot, J. P. Sabate
Publikováno v:
Toxicological Sciences. 45:212-224
Autor:
Dominique Beydon, Anne-Marie Saillenfait, J. P. Payan, Jean-Philippe Sabaté, J. P. Fabry, I. Langonne, F. Gallissot
Publikováno v:
Toxicological Sciences. 39:33-43
This study evaluates the developmental toxicity and placental and milk transfer of N,N-dimethylformamide (DMF) in rats. Sprague-Dawley rats were given 0, 50, 100, 200, and 300 mg DMF/kg/day, by gavage, on Gestational Days (GD) 6 through 20. Maternal
Publikováno v:
The Journal of Immunology. 154:1097-1104
CD43 is a major membrane sialoglycoprotein expressed by cells of hematopoietic origin. One property of CD43 is its ability to interfere with heterotypic and homotypic cellular adhesion. To determine whether CD43 expression can affect cell functions r
Publikováno v:
Journal of Applied Toxicology. 13:19-24
Male Sprague Dawley rats with cannulated bile duct (BDC rats) received 100 or 200 mg kg-1 labelled hexachloro-1,3-butadiene ([14C]HCBD) by gavage 1 h (BDC1 rats) or 24 h (BDC24 rats) after surgical cannula implantation. Twenty-four hours after treatm
Autor:
J P, Payan, J P, Marty, J P, Fabry, D, Beydon, I, Boudry, E, Ferrari, F, Canel, M C, Grandclaude, C M, Vincent
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 29(6)
This study evaluated the toxicokinetics of [(14)C]di-n-butylphthalate ([(14)C]DBP) after an intravenous administration (1 and 10 mg/kg, in Cremophor) or a topical application (10 microl/cm(2); 10 cm(2), neat) in haired male Sprague-Dawley rats. Addit
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 29(6)
In a previous study, it was shown that the neurotoxic compound 1,2-diethylbenzene (1,2-DEB) is mainly hydroxylated in the alkyl chain to give 1-(2'-ethylphenyl)ethanol (1,2-EPE) and excreted in urine of rats as two glucuronide compounds (GA1 and GA2)
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 27(12)
The excretion and metabolism of neurotoxic 1,2-diethylbenzene (1, 2-DEB) was studied in male Sprague-Dawley rats after i.v. (1 mg/kg) or oral (1 or 100 mg/kg) administration of 1,2-diethyl[U-(14)C]benzene ([(14)C]1,2-DEB). Whatever the treatment, rad
Autor:
F. Gallissot, Dominique Beydon, Jean-Philippe Sabaté, J. P. Fabry, Anne-Marie Saillenfait, I. Langonne, J. P. Payan
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 45(2)
The developmental toxicity and placental transfer of di-n-butyl phthalate (DBP) were evaluated in Sprague-Dawley rats given a single oral dose of DBP on Gestational Day 14. In the developmental toxicity study, dams were dosed with 0, 0.5, 1, 1.5, or
Publikováno v:
Blood. 90(6)
We infused six human immunodeficiency virus (HIV)-seropositive subjects with autologous CD8+ cytotoxic T cells (CTLs) enriched for HIV-specific cytotoxicity targeted against a diversity of HIV epitopes in gp120, gag p17 and p24, and nef. There was no