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pro vyhledávání: '"J A Doebler"'
Autor:
J A Doebler
Publikováno v:
Cell Biology and Toxicology. 15:279-289
Studies were conducted using a novel in vitro approach to investigate the efficacy of acetamidine hydrochloride (ACE) and guanidine hydrochloride (GUAN), previously shown to block gramicidin D (GRAM) channels in artificial membranes, in preventing th
Autor:
J A, Doebler
Publikováno v:
Neurochemical research. 25(7)
The NG 108-15 (neuroblastoma X glioma hybrid) cell line was used as an in vitro neuronal model to evaluate potential antagonists of the Na+-selective carboxylic ionophore monensin. Changes in membrane electrical characteristics induced by monensin wi
Autor:
J A, Doebler
Publikováno v:
Cell biology and toxicology. 15(5)
Studies were conducted using a novel in vitro approach to investigate the efficacy of acetamidine hydrochloride (ACE) and guanidine hydrochloride (GUAN), previously shown to block gramicidin D (GRAM) channels in artificial membranes, in preventing th
Autor:
J A, Doebler
Publikováno v:
Neurochemical research. 25(2)
Studies were conducted to determine the effects of bath application of the protonophores carbonyl cyanide m-chlorophenylhydrazone (CCCP) and carbonyl cyanide p-(trifluoromethoxy)-phenylhydrazone (FCCP) on membrane electrical characteristics of differ
Publikováno v:
Journal of Histochemistry & Cytochemistry. 29:1164-1170
A procedure entailing the use of the Feulgen reaction is described for precise quantification of nuclear DNA levels in smooth muscle cells (SMC) of paraffin-processed microtome sections of the rabbit aorta. It was established that maximal, stable, an
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 46:28-39
Topographic analyses were performed on the distribution of neuronal RNA loss in relation to local neuronal loss and neurofibrillary degeneration in the hippocampal region of brains of patients with Alzheimer's disease (AD). Compared to age-matched co
Publikováno v:
Neurology. 37(2)
Scanning-integrating microdensitometry of azure B-RNA- and Feulgen-Schiff-stained tissue sections was used to measure neostriatal neuronal RNA levels and susceptibility of neuronal and oligodendrocyte chromatin to acid hydrolysis in Alzheimer's disea
Autor:
J A, Doebler, A, Anthony
Publikováno v:
Artery. 13(4)
Microfluorimetric and quantitative cytoenzymatic techniques were employed to examine regional variations in endothelial macromolecular uptake as related to inner mural intermediary metabolism in aortas from normocholesterolemic rabbits. Concomitant r
Publikováno v:
Acta neuropathologica. 75(3)
A new double-staining procedure, in which the techniques of immunocytochemistry of glial fibrillary acidic protein (GFAP) and quantitative microdensitometry of azure B-RNA were combined, was used to study nucleic acid alterations in fibrous astrocyte
Publikováno v:
Experientia. 41:1457-1458
Effects of the organophosphate neurotoxin soman on rat mesenteric mast cell granule content were determined using scanning-integrating microdensitometric analysis of individual cell metachromasia. Mast cell degranulation was evidenced both with suble