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Autor:
J, Dulos, F P G, Wijnands, J A J, van den Hurk-van Alebeek, M J H, van Vugt, J A C, Rullmann, J-J G, Schot, M W G D M, de Groot, J L, Wagenaars, R, van Ravestein-van Os, R L, Smets, P M, Vink, C L, Hofstra, R L H, Nelissen, H, van Eenennaam
Publikováno v:
Clinical and experimental rheumatology. 31(4)
For many years the p38 MAP kinase (MAPK) has been a major anti-inflammatory target for the development of an oral therapy for rheumatoid arthritis (RA). However, disappointing results from Phase II clinical studies suggest that adaptations may occur,