Zobrazeno 1 - 7 of 7 pro vyhledávání: '"J A Behrle"'
1
The pharmacokinetics and safety of desvenlafaxine in subjects with chronic renal impairment
Autor: Lyette S Richards, S. B. McGrory, Jeffrey Paul, J A Posener, J A Behrle, Alice I. Nichols
Publikováno v: International journal of clinical pharmacology and therapeutics. 49(1)
BACKGROUND Desvenlafaxine (administered as desvenlafaxine succinate), the major active metabolite of venlafaxine, is a new serotonin-norepinephrine reuptake inhibitor (SNRI) approved for the treatment of major depressive disorder (MDD). OBJECTIVE To
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d916551996ab8262f473676124e17150
https://pubmed.ncbi.nlm.nih.gov/21176719
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4
An open-label, randomized, single-dose, dose-proportionality study of oral doses of a sustained-release formulation of desvenlafaxine succinate in healthy subjects
Autor: J. A. Behrle, Alice I. Nichols, D. Raible, S. B. McGrory
Publikováno v: Clinical Pharmacology & Therapeutics. 77:P82-P82
Background/Aims To assess the dose-proportionality of single oral doses of a sustained-release formulation of desvenlafaxine succinate (DVS-SR) in healthy subjects. Methods A randomized single-dose crossover study was conducted in 24 healthy male sub
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::29c38d2f4794754559b2f91a2c26ca66
https://doi.org/10.1016/j.clpt.2004.12.207
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5
Safety, pharmacokinetics (<>Pk) and pharmacodynamics (PD) of ascending single oral doses of sustained-release desvenlafaxine succinate (DVS-SR) in healthy subjects
Autor: J. H. Decours, Alain Patat, J. A. Behrle, V. Parks, S. M. Troy
Publikováno v: Clinical Pharmacology & Therapeutics. 77:P44-P44
Background/Aims To assess the safety, tolerability, PK and PD of ascending single oral doses of DVS-SR in healthy subjects. Methods This was a randomized, placebo-controlled, ascending single dose study in 79 healthy male subjects. Doses of 150, 225,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a57792c3cad025f891e00c042ddc0bc4
https://doi.org/10.1016/j.clpt.2004.12.063
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6
An open-label, randomized, crossover study of the relative bioavailability of desvenlafaxine after oral administration of extended-release venlafaxine and sustained-release desvenlafaxine succinate in healthy subjects
Autor: Alice I. Nichols, J. A. Behrle, A. Patat, P. Chretien, S. Baird‐Bellaire
Publikováno v: Clinical Pharmacology & Therapeutics. 77:P86-P86
Background/Aims To assess the relative bioavailability of desvenlafaxine (DV) after single oral doses of extended-release venlafaxine (VEN-ER) and sustained-release desvenlafaxine succinate (DVS-SR) in healthy subjects. Methods A randomized single-do
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::18a75092ef8c57fdc3438ca92f79c198
https://doi.org/10.1016/j.clpt.2004.12.222
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7
An ascending multiple-dose study of the safety and pharmacokinetics of a sustained-release formulation of desvenlafaxine succinate in healthy subjects
Autor: Jeffrey Paul, Lyette S Richards, Alice I. Nichols, J. A. Behrle, Richard Fruncillo
Publikováno v: Clinical Pharmacology & Therapeutics. 77:P84-P84
Background/Aims To assess the safety, tolerability, and pharmacokinetics (PK) of ascending multiple oral doses of a sustained-release formulation of desvenlafaxine succinate (DVS-SR) in healthy subjects. Methods A randomized, placebo-controlled, asce
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aacf12f28eda6f8bdf156419326ed4d3
https://doi.org/10.1016/j.clpt.2004.12.215
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