Zobrazeno 1 - 10
of 695
pro vyhledávání: '"J A, Nieto"'
Autor:
N. L. Ramírez-Serrato, J. J. Nieto-Butrón, S. Barco-Coyote, F. D. Yépez-Rincon, M. P. Jácome Paz
Publikováno v:
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, Vol XLVIII-3-2024, Pp 453-458 (2024)
Flooding poses a persistent threat to urban areas, prompting the use of mathematical modeling to understand flow dynamics and delineate flood zones. Integrating vegetation into hydraulic models is crucial for assessing its effects on flow characteris
Externí odkaz:
https://doaj.org/article/59a24513dea64e8187d537c19f283df3
Autor:
Andrea Herencia-Ropero, Alba Llop-Guevara, Anna D. Staniszewska, Joanna Domènech-Vivó, Eduardo García-Galea, Alejandro Moles-Fernández, Flaminia Pedretti, Heura Domènech, Olga Rodríguez, Marta Guzmán, Enrique J. Arenas, Helena Verdaguer, Fernando J. Calero-Nieto, Sara Talbot, Luis Tobalina, Elisabetta Leo, Alan Lau, Paolo Nuciforo, Rodrigo Dienstmann, Teresa Macarulla, Joaquín Arribas, Orland Díez, Sara Gutiérrez-Enríquez, Josep V. Forment, Mark J. O’Connor, Mark Albertella, Judith Balmaña, Violeta Serra
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Poly (ADP-ribose) polymerase 1 and 2 (PARP1/2) inhibitors (PARPi) are targeted therapies approved for homologous recombination repair (HRR)-deficient breast, ovarian, pancreatic, and prostate cancers. Since inhibition of PARP1 is
Externí odkaz:
https://doaj.org/article/68b3f150f248467b98d10c77d2ec9d7a
Autor:
P. M. García-Meneses, R. García-Herrera, F. Serrano-Candela, L. Charli-Joseph, J. Mota-Nieto, J. D. Mejía Ciro, E. Platas-Valle, S. Garcilita-Arguello, A. Fernández-Reyes, A. Toriz Cruz, J. A. Corona-Jiménez
Publikováno v:
Frontiers in Sustainability, Vol 5 (2024)
Envisioning trajectories towards sustainability encompasses enacting significant changes in multiple spheres (i.e., infrastructure, policy, practices, behaviors). These changes unfold within the intricate landscapes of wicked problems, where diverse
Externí odkaz:
https://doaj.org/article/bc8e956a53fd4ac2995a290e7a51415f
Autor:
Elizabeth L. Hardaker, Emilio Sanseviero, Ankur Karmokar, Devon Taylor, Marta Milo, Chrysis Michaloglou, Adina Hughes, Mimi Mai, Matthew King, Anisha Solanki, Lukasz Magiera, Ricardo Miragaia, Gozde Kar, Nathan Standifer, Michael Surace, Shaan Gill, Alison Peter, Sara Talbot, Sehmus Tohumeken, Henderson Fryer, Ali Mostafa, Kathy Mulgrew, Carolyn Lam, Scott Hoffmann, Daniel Sutton, Larissa Carnevalli, Fernando J. Calero-Nieto, Gemma N. Jones, Andrew J. Pierce, Zena Wilson, David Campbell, Lynet Nyoni, Carla P. Martins, Tamara Baker, Gilberto Serrano de Almeida, Zainab Ramlaoui, Abdel Bidar, Benjamin Phillips, Joseph Boland, Sonia Iyer, J. Carl Barrett, Arsene-Bienvenu Loembé, Serge Y. Fuchs, Umamaheswar Duvvuri, Pei-Jen Lou, Melonie A. Nance, Carlos Alberto Gomez Roca, Elaine Cadogan, Susan E. Critichlow, Steven Fawell, Mark Cobbold, Emma Dean, Viia Valge-Archer, Alan Lau, Dmitry I. Gabrilovich, Simon T. Barry
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The Ataxia telangiectasia and Rad3-related (ATR) inhibitor ceralasertib in combination with the PD-L1 antibody durvalumab demonstrated encouraging clinical benefit in melanoma and lung cancer patients who progressed on immunotherapy. Here we
Externí odkaz:
https://doaj.org/article/189773f2417346dcbdf8b6281d57effa
Autor:
Roshana Thambyrajah, Maria Maqueda, Wen Hao Neo, Kathleen Imbach, Yolanda Guillén, Daniela Grases, Zaki Fadlullah, Stefano Gambera, Francesca Matteini, Xiaonan Wang, Fernando J. Calero-Nieto, Manel Esteller, Maria Carolina Florian, Eduard Porta, Rui Benedito, Berthold Göttgens, Georges Lacaud, Lluis Espinosa, Anna Bigas
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Hematopoietic stem cells (HSCs) develop from the hemogenic endothelium (HE) in the aorta- gonads-and mesonephros (AGM) region and reside within Intra-aortic hematopoietic clusters (IAHC) along with hematopoietic progenitors (HPC). The signal
Externí odkaz:
https://doaj.org/article/89ff244b2ed24e0cb8b752459be716ea
Publikováno v:
Frontiers in Applied Mathematics and Statistics, Vol 10 (2024)
We describe the genetic code in terms of numbers that help us to find several dual symmetries. Our formulation can even be rewritten regarding the up-down and right-left dual concepts. We argue that our work may bring many topological tools to studyi
Externí odkaz:
https://doaj.org/article/f292c07a8ffc451fba80e624f1d17690
Publikováno v:
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, Vol XLVIII-M-2-2023, Pp 1089-1096 (2023)
The conservation of cultural heritage can be affected by different changes in temperature and humidity within architectural spaces, so energy performance and interior microclimate of historic buildings require adaptation to new maintenance and preven
Externí odkaz:
https://doaj.org/article/9c2e0a89f77244698f9e684985e4f297
Autor:
M. D. Robador González, J. E. Nieto-Julián, P. M. Millán-Millán, A. Galera-Rodríguez, S. Bruno, D. Debenedictis, J. Moyano
Publikováno v:
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, Vol XLVIII-M-2-2023, Pp 1323-1330 (2023)
Historic Building Information Modelling (HBIM) has become the ideal tool for professionals studying building conservation and restoration. The BIM model allows one to identify structural deformations following three-dimensionally resolved models. In
Externí odkaz:
https://doaj.org/article/248fa58793d34bbc8dcf7e09f312b488
Autor:
Martin Potts, Alice Fletcher-Etherington, Katie Nightingale, Federica Mescia, Laura Bergamaschi, Fernando J. Calero-Nieto, Robin Antrobus, James Williamson, Harriet Parsons, Edward L. Huttlin, Nathalie Kingston, Berthold Göttgens, John R. Bradley, Paul J. Lehner, Nicholas J. Matheson, Kenneth G.C. Smith, Mark R. Wills, Paul A. Lyons, Michael P. Weekes
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112613- (2023)
Summary: Certain serum proteins, including C-reactive protein (CRP) and D-dimer, have prognostic value in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Nonetheless, these factors are non-specific, providing limited mecha
Externí odkaz:
https://doaj.org/article/c7326025d3cb4f20b0a4a053867e6734
Publikováno v:
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, Vol XLVI-5-W1-2022, Pp 199-204 (2022)
In recent years there has been a great effort by the agents of the AECO sector aimed at an efficient use of data interoperability between the participating disciplines and the applicability in the specific software. In this context, the BIM (Building
Externí odkaz:
https://doaj.org/article/b6a63fc2e4da4b17a1c3334a332ef62e