Zobrazeno 1 - 10
of 32
pro vyhledávání: '"J A, Messias"'
Autor:
Hellen Weinschutz Mendes, Angelica Beate Winter Boldt, Ewalda von Rosen Seeling Stahlke, Jens Christian Jensenius, Steffen Thiel, Iara J Taborda Messias-Reason
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 4, p e0007534 (2020)
BackgroundDeposition of complement factors on Mycobacterium leprae may enhance phagocytosis. Such deposition may occur through the lectin pathway of complement. Three proteins of the lectin pathway are produced from the gene MASP1: Mannan-binding lec
Externí odkaz:
https://doaj.org/article/9c96f48bc16b48789d23f72f9070285d
Autor:
Maria Regina Tizzot, Kárita Cláudia Freitas Lidani, Fabiana Antunes Andrade, Hellen Weinschutz Mendes, Marcia Holsbach Beltrame, Edna Reiche, Steffen Thiel, Jens C. Jensenius, Iara J. de Messias-Reason
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The complement system is a key component of the innate immune system, participating in the surveillance against infectious agents. Once activated by one of the three different pathways, complement mediates cell lysis, opsonization, signalizes pathoge
Externí odkaz:
https://doaj.org/article/d2ad2e0278b54af88da397f4881be77e
Autor:
Elidiana De Bona, Kárita Cláudia Freitas Lidani, Lorena Bavia, Zahra Omidian, Luiza Helena Gremski, Thaisa Lucas Sandri, Iara J. de Messias Reason
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Chagas disease (CD), a neglected tropical disease caused by the protozoan Trypanosoma cruzi, affects around six million individuals in Latin America. Currently, CD occurs worldwide, becoming a significant public health concern due to its silent aspec
Externí odkaz:
https://doaj.org/article/73586cb238a14ea1b1debf3db305f442
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Trypanosoma cruzi is a protozoan parasite known to cause Chagas disease (CD), a neglected sickness that affects around 6–8 million people worldwide. Originally, CD was mainly found in Latin America but more recently, it has been spread to countries
Externí odkaz:
https://doaj.org/article/7913ec1f18644a41a92a89ff3ed4cbb9
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 109, Iss 4, Pp 442-447 (2014)
The aim of the present study was to detect natural infection by Leishmania (Leishmania) infantum in Lutzomyia longipalpis captured in Barcarena, state of Pará, Brazil, through the use of three primer sets. With this approach, it is unnecessary to pr
Externí odkaz:
https://doaj.org/article/01aaabb2e2104919a3a9e1ac433925ee
Autor:
Isabela Goeldner, Thelma L Skare, Shirley R Utiyama, Renato M Nisihara, Hoang van Tong, Iara J T Messias-Reason, Thirumalaisamy P Velavan
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95519 (2014)
INTRODUCTION: Rheumatoid arthritis (RA) is a commonly occurring systemic inflammatory auto immune disease and is believed to be associated with genetic factors. The innate immune complement protein Mannose binding lectin (MBL) and their MBL2 genetic
Externí odkaz:
https://doaj.org/article/552cfcc7306f409e802beaad7574d499
Autor:
Paola R Luz, Angelica B W Boldt, Caroline Grisbach, Jürgen F J Kun, Thirumalaisamy P Velavan, Iara J T Messias-Reason
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60237 (2013)
BackgroundL-ficolin (encoded by FCN2) binds to acetylated sugar moieties of many pathogens, including Trypanosoma cruzi, promoting their phagocytosis and lysis by the complement system.MethodsWe investigated L-ficolin levels in 160 T. cruzi infected
Externí odkaz:
https://doaj.org/article/7ba6002344eb4bd6a08b951ffdefa543
Autor:
Aditya Nath Jha, Vipin Kumar Singh, Namrata Kumari, Ashish Singh, Justin Antony, Hoang van Tong, Sakshi Singh, Sudhanshu S Pati, Pradeep K Patra, Rajender Singh, Nguyen L Toan, Le H Song, Amal Assaf, Iara J T Messias-Reason, Thirumalaisamy P Velavan, Lalji Singh, Kumarasamy Thangaraj
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48136 (2012)
BACKGROUND: Interleukin 4 (IL-4) is an anti-inflammatory cytokine, which regulates balance between T(H)1 and T(H)2 immune response, immunoglobulin class switching and humoral immunity. Polymorphisms in this gene have been reported to affect the risk
Externí odkaz:
https://doaj.org/article/f06c2d5051fd43b099e41466843cc140
Human complement receptor type 1 (CR1) protein levels and genetic variants in chronic Chagas Disease
Autor:
Thaisa Lucas, Sandri, Kárita Cláudia Freitas, Lidani, Fabiana Antunes, Andrade, Christian G, Meyer, Peter G, Kremsner, Iara J, de Messias-Reason, Thirumalaisamy P, Velavan
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Complement is an essential element in both innate and acquired immunity contributing to the immunopathogenesis of many disorders, including Chagas Disease (CD). Human complement receptor 1 (CR1) plays a role in the clearance of complement opsonized m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c354cbdcd7f8747854eef04a7d5816b4
Autor:
M I, Ramirez, P, Deolindo, I J, de Messias-Reason, Emma A, Arigi, H, Choi, I C, Almeida, I, Evans-Osses
Publikováno v:
Cellular microbiology. 19(4)
Extracellular vesicles released from pathogens may alter host cell functions. We previously demonstrated the involvement of host cell-derived microvesicles (MVs) during early interaction between Trypanosoma cruzi metacyclic trypomastigote (META) stag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d690c3866d4fdb36fc20ca7f31241db3
https://pubmed.ncbi.nlm.nih.gov/27665486
https://pubmed.ncbi.nlm.nih.gov/27665486