Výsledky vyhledávání - "J A, Langermans"

IFN-gamma-induced L-arginine-dependent toxoplasmastatic activity in murine peritoneal macrophages is mediated by endogenous tumor necrosis factor-alpha

Autor: J A Langermans, M E Van der Hulst, P H Nibbering, P S Hiemstra, L Fransen, R Van Furth

Publikováno v: The Journal of Immunology. 148:568-574

Activated murine peritoneal macrophages inhibit the intracellular proliferation of Toxoplasma gondii and produce a number of cytokines, such as TNF-alpha and IL-1. Both TNF-alpha and IL-1 have been reported to be involved in the immune response again

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ce75c378543fb3cb1373da4c34dd6319
https://doi.org/10.4049/jimmunol.148.2.568

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Activation of mouse peritoneal macrophages during infection with Salmonella typhimurium does not result in enhanced intracellular killing

Autor: J A Langermans, M E van der Hulst, P H Nibbering, R van Furth

Publikováno v: The Journal of Immunology. 144:4340-4346

Our study was performed to investigate whether macrophages become activated during an infection with Salmonella typhimurium and, if so, whether these activated macrophages kill S. typhimurium faster than resident macrophages. Mice received i.v. injec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fc4831dffaba8c50c2dc9a29273e4a72
https://doi.org/10.4049/jimmunol.144.11.4340

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Transforming growth factor-beta suppresses interferon-gamma-induced toxoplasmastatic activity in murine macrophages by inhibition of tumour necrosis factor-alpha production

Autor: J A, Langermans, P H, Nibbering, M E, Van Vuren-Van Der Hulst, R, Van Furth

Publikováno v: Parasite immunology. 23(4)

Activation of macrophages plays an important role in the host resistance against intracellular pathogens. Various mechanisms are employed to control the activation processes and limit tissue damage by factors produced by activated macrophages. One of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ac66f5953f12b46286d1db284f17aad5
https://pubmed.ncbi.nlm.nih.gov/11298293

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Protection against Plasmodium falciparum malaria in chimpanzees by immunization with the conserved pre-erythrocytic liver-stage antigen 3

Autor: P, Daubersies, A W, Thomas, P, Millet, K, Brahimi, J A, Langermans, B, Ollomo, L, BenMohamed, B, Slierendregt, W, Eling, A, Van Belkum, G, Dubreuil, J F, Meis, C, Guérin-Marchand, S, Cayphas, J, Cohen, H, Gras-Masse, P, Druilhe, L B, Mohamed

Publikováno v: Nature medicine. 6(11)

In humans, sterile immunity against malaria can be consistently induced through exposure to the bites of thousands of irradiated infected mosquitoes. The same level of protection has yet to be achieved using subunit vaccines. Recent studies have indi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f282da35be26eb72d26599841626c73a
https://pubmed.ncbi.nlm.nih.gov/11062530

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Genetic influence on cytokine production and fatal meningococcal disease

Autor: R G, Westendorp, J A, Langermans, T W, Huizinga, A H, Elouali, C L, Verweij, D I, Boomsma, J P, Vandenbroucke, J P, Vandenbrouke

Publikováno v: Westendorp, R G J, Langermans, J A M, Huizinga, T W J, Elouali, A H, Verweij, C L, Boomsma, D I & Vandenbroucke, J P 1997, ' Genetic influence on cytokine production and fatal meningococcal disease ', Lancet, vol. 349, no. 9046, pp. 170-173 . https://doi.org/10.1016/S0140-6736(96)06413-6
Lancet, 349(9046), 170-173. Elsevier Limited

Summary Background To assess the genetic influence on cytokine production and its contribution to fatal outcome, we determined the capacity to produce tumour necrosis factor-α (TNFα) and interleukin-10 (IL-10) in families of patients who had had me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0409488fedee283191e613ed246a6027
https://pubmed.ncbi.nlm.nih.gov/9217780

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Tumour necrosis factor, but not interferon-gamma, is essential for acquired resistance to Listeria monocytogenes during a secondary infection in mice

Autor: J N, Samsom, J A, Langermans, H F, Savelkoul, R, van Furth

Publikováno v: Immunology. 86(2)

Mice with a secondary Listeria monocytogenes infection eliminate the bacteria much faster and more efficiently from their organs than mice with a primary infection. During the course of a secondary infection, serum concentrations of interferon-gamma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::db881bf8b9564bc3347a33258f3a2ecc
https://pubmed.ncbi.nlm.nih.gov/7490127

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Effect of IFN-gamma and endogenous TNF on the histopathological changes in the liver of Listeria monocytogenes-infected mice

Autor: J A, Langermans, D M, Mayanski, P H, Nibbering, M E, van der Hulst, J S, van de Gevel, R, van Furth

Publikováno v: Immunology. 81(2)

During primary infection of mice with Listeria monocytogenes, the bacteria proliferate extensively in the liver resulting in the development of inflammatory lesions in this organ. In the present study, the effect of interferon-gamma (IFN-gamma) on th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c8a84a1219b51434c0a260141871bb85
https://pubmed.ncbi.nlm.nih.gov/8157268

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Intravenous injection of interferon-gamma inhibits the proliferation of Listeria monocytogenes in the liver but not in the spleen and peritoneal cavity

Autor: J A, Langermans, M E, van der Hulst, P H, Nibbering, P H, van der Meide, R, van Furth

Publikováno v: Immunology. 77(3)

In the present study the effects of intravenous administration of recombinant interferon-gamma (IFN-gamma) on both the proliferation of Listeria monocytogenes in the liver and spleen of mice and the listericidal activity of their peritoneal macrophag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0b3e704c687e7a24b360850888159024
https://pubmed.ncbi.nlm.nih.gov/1478682

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IFN-gamma-induced L-arginine-dependent toxoplasmastatic activity in murine peritoneal macrophages is mediated by endogenous tumor necrosis factor-alpha

Autor: J A, Langermans, M E, Van der Hulst, P H, Nibbering, P S, Hiemstra, L, Fransen, R, Van Furth

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 148(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::24e17b44a045118adf688abe3f1bbf27
https://pubmed.ncbi.nlm.nih.gov/1729374

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