Zobrazeno 1 - 10
of 23
pro vyhledávání: '"J A, Hubácek"'
Publikováno v:
International angiology : a journal of the International Union of Angiology. 30(3)
The aim of our study was to evaluate a possible association between subclinical atherosclerosis in carotid arteries and the connexin 37 gene polymorphism (1019CT; Pro319Ser) in a population of urban and rural women.A 5% population sample of urban wom
Publikováno v:
Folia biologica. 55(3)
Coronary artery disease is a serious health problem worldwide caused by interactions between genetic and environmental risk factors. One of the candidate genes is the gene for apolipoprotein E. We present a case report of two young smoking and obese
Autor:
J A, Hubácek, V, Adámková, K, Zídková, R, Ceska, L, Zlatohlávek, T, Stulc, A, Horínek, M, Vrablík
Publikováno v:
Vnitrni lekarstvi. 54(1)
Reducing high levels of plasmatic lipoids (LDL-cholesterol and triglycerides) is one of the most important steps in the prevention and treatment of cardiovascular diseases. In the majority of cases, treatment based on lifestyle changes (changes in di
Publikováno v:
Folia biologica. 54(1)
PHHC rats represent a suitable experimental model of polygenic hypercholesterolemia. It has been found that its metabolic defect is not related to alimentary cholesterol absorption and LDL clearance. We have tested possible changes in cholesterol cle
Publikováno v:
Folia biologica. 53(6)
Ghrelin is a hormone which influences eating habits, the amount of food ingested and the body's energy balance. We examined whether genetic variants in the ghrelin gene are associated with BMI, WHR and plasma lipid levels. We have evaluated the influ
Autor:
J A, Hubácek, M, Vrablík
Publikováno v:
Vnitrni lekarstvi. 53(4)
The great majority of plasmatic lipid and lipoprotein metabolism disorders are genetically determined diseases (primary dyslipidemias). Only a minority of prevailingly severe dyslipidemias is monogenic, and a greater part of them is inherited as a po
Publikováno v:
Physiological research. 54(6)
The important role of APOAV gene variants in determination of plasma triglyceride levels has been shown in many population studies. Recently, an influence of APOAV T-1131C polymorphism on C-reactive protein (CRP) in young Korean males has been report
Autor:
J A, Hubácek, M, Weichetová
Publikováno v:
Casopis lekaru ceskych. 144(1)
Osteoporosis is a chronic progressive disease, characterized by higher bone resorption than bone mass accumulation. This leads to reduction of the bone mass, to microarchitectural deterioration of the bone tissue and to the increased risk of bone fra
Autor:
J A, Hubácek
Publikováno v:
Casopis lekaru ceskych. 143(12)
High plasma triglyceride levels have been suggested to be independent risk factors of cardiovascular disease development and cardiovascular diseases are the most common cause of death in industrial countries around the world. It is known, that plasma
Publikováno v:
Physiological research. 54(5)
Through the analysis of the common apolipoprotein (apo) E gene polymorphism in large Caucasian population study with the PCR and subsequent restriction analysis, we have identified carriers of mutant allele Arg136--Ser. Both of them (71-years-old fem