Zobrazeno 1 - 10
of 17
pro vyhledávání: '"J A, Hobden"'
Autor:
Laura G. Alionte, Armando R. Caballero, J A Hobden, Benetta M. Cannon, Catherine D. White, Richard J. O'Callaghan
Publikováno v:
Cornea. 20:643-646
Purpose Pseudomonas aeruginosa PAO1 deficient in LasA protease was reported to be ocularly avirulent. However, the avirulence of this mutant could not attributed to the loss of LasA protease. The purpose of this study was to define the mechanism for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e744e39ba3b63ff92e22a9238e5e0b8
https://doi.org/10.1097/00003226-200108000-00017
https://doi.org/10.1097/00003226-200108000-00017
Publikováno v:
Antimicrobial Agents and Chemotherapy. 37:1856-1859
This study was conducted to determine whether the age of the host influences the pathogenesis and therapeutic outcome of drug-treated Pseudomonas aeruginosa keratitis. Young (3- to 5-month-old) and old (1.5- to 3-year-old) rabbits were intrastromally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac74b5072e076215581b07f4d716e85
https://doi.org/10.1128/aac.37.9.1856
https://doi.org/10.1128/aac.37.9.1856
Publikováno v:
Cornea. 12:138-141
To compare the efficacy of ciprofloxacin hydrochloride ointment with that of ciprofloxacin drops for treatment of experimental Pseudomonas keratitis, rabbit eyes were infected by intrastromal injection of 10(3) colony-forming units (CFU) log-phase P.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55cf5e4d658da6e104ae0dd73e12f278
https://doi.org/10.1097/00003226-199303000-00008
https://doi.org/10.1097/00003226-199303000-00008
Publikováno v:
International Ophthalmology Clinics. 33:69-80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50d9188064d364496a8282cbf4622746
https://doi.org/10.1097/00004397-199303340-00008
https://doi.org/10.1097/00004397-199303340-00008
Publikováno v:
Current eye research. 21(3)
Alkaline protease has been associated with virulence in Pseudomonas aeruginosa corneal infections. To define the role of this enzyme in such infections, isogenic mutants of P. aeruginosa deficient in alkaline protease production were constructed. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::03b5fc33bf534d14453b57b451ae8ac6
https://pubmed.ncbi.nlm.nih.gov/11120561
https://pubmed.ncbi.nlm.nih.gov/11120561
Publikováno v:
Current eye research. 20(3)
Pseudomonas aeruginosa proteases are thought to be important virulence factors in the pathogenesis of corneal disease. This study examined protease production from two strains of P. aeruginosa responsible for two very distinct clinical diseases: stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e66b85b9f3104c97b3a1f45214a8220
https://pubmed.ncbi.nlm.nih.gov/10694889
https://pubmed.ncbi.nlm.nih.gov/10694889
Publikováno v:
Investigative ophthalmologyvisual science. 39(3)
A Pseudomonas mutant deficient in protease IV has significantly reduced virulence in experimental keratitis. In the present study, the corneal toxicity of purified protease IV and its ability to augment the virulence of protease-IV-deficient bacteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c2f113a074ad9bddc186ae851f94d0e
https://pubmed.ncbi.nlm.nih.gov/9501882
https://pubmed.ncbi.nlm.nih.gov/9501882
Publikováno v:
Investigative ophthalmologyvisual science. 38(8)
The role of protease IV in the pathogenesis of Pseudomonas aeruginosa keratitis was investigated by comparing a mutant strain completely deficient in protease IV activity with its protease IV activity-producing parent.A protease IV-deficient Pseudomo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fec64ba460c57ef117e877d2f89ea710
https://pubmed.ncbi.nlm.nih.gov/9224281
https://pubmed.ncbi.nlm.nih.gov/9224281
Publikováno v:
Investigative ophthalmologyvisual science. 37(4)
The role of exoproteins in the pathogenesis of Pseudomonas aeruginosa keratitis was investigated in three animal models by assessing the relationship between corneal virulence and the activities of exotoxin A, elastase, alkaline protease, and an unch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::900c721ad96e661906850351a767c1a5
https://pubmed.ncbi.nlm.nih.gov/8595953
https://pubmed.ncbi.nlm.nih.gov/8595953
Publikováno v:
Investigative ophthalmologyvisual science. 36(7)
To establish if active pseudomonal proteases are present in vivo during corneal infection with Pseudomonas aeruginosa and to determine if the mouse strains used in these and previous studies have the ability to mount a nonocular antibody response to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c2a97b6b30db89f35c21d3f62ca2fdc2
https://pubmed.ncbi.nlm.nih.gov/7775115
https://pubmed.ncbi.nlm.nih.gov/7775115