Zobrazeno 1 - 10 of 84 pro vyhledávání: '"J A, Haseman"'
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USING THE NTP DATABASE TO ASSESS THE VALUE OF RODENT CARCINOGENICITY STUDIES FOR DETERMINING HUMAN CANCER RISK
Autor: J. K. Haseman
Publikováno v: Drug Metabolism Reviews. 32:169-186
The large database of carcinogenicity results generated by the National Toxicology Program (NTP) provides a unique opportunity to critically evaluate important scientific issues such as (1) the frequency of positive outcomes, (2) the interspecies cor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f52c98851ba8d48b85c8998bf13f297b
https://doi.org/10.1081/dmr-100100570
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3
Modeling Tumor Onset and Multiplicity Using Transition Models with Latent Variables
Autor: J. K. Haseman, David B. Dunson
Publikováno v: Biometrics. 55:965-970
Summary. We describe a method for modeling carcinogenicity from animal studies where the data consist of counts of the number of tumors present over time. The research is motivated by applications to transgenic rodent studies, which have emerged as a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f915701f5a3a72c8791952b1d49f1d25
https://doi.org/10.1111/j.0006-341x.1999.00965.x
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6
Evaluation of False Positive and False Negative Outcomes in NTP Long-Term Rodent Carcinogenicity Studies
Autor: M. R. Elwell, J. K. Haseman
Publikováno v: Risk Analysis. 16:813-820
The decision-making process used by the National Toxicology Program (NTP) in its evaluation of long-term rodent carcinogenicity studies was investigated to determine whether or not this procedure resulted in an excessive number of false positive or f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4077c0f9fd0b2d0dbdd9c8eb7c02f9f
https://doi.org/10.1111/j.1539-6924.1996.tb00832.x
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